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07 November 2019 | Story Thabo Kessah | Photo Johan Roux
Qwaqwa Campus top academic achiever, Selloane Mile, with Campus Principal, Dr Martin Mandew.
Qwaqwa Campus top academic achiever, Selloane Mile, with Campus Principal, Dr Martin Mandew.

Bosso ke mang? So goes a popular township saying derived from the late Hip Hop Pantsula’s (HHP) hit track, Bosso. Literally, it means ‘who is the boss?’

Selloane Mile, the 2018/2019 SRC Secretary General for the Qwaqwa Campus, was a tutor in the Faculties of Education and the Humanities from 2017 to 2019, and is also an aspiring poet and author. She is now the Qwaqwa Campus Dux Student for 2019, with an average of 84, 3%.

“I am very honoured and humbled to have been bestowed the award as the best academic student on the Qwaqwa Campus at the recent Student Excellence Awards ceremony. The experience certainly feels unreal and I am yet to come to terms with the magnitude of this accolade,” said Selloane, a final-year Bachelor of Education (Senior Phase and FET) student. 

The secret is, there is no secret

When asked what her secret was, she said: “I do not think there is any secret or technique that I can attribute my academic achievements to. However, I think setting a standard for yourself and being consistent in whatever we do to realise those standards we have set for ourselves, is the key to success. Also important is flexibility. One has to give yourself the chance to explore and tap into different horizons.” 

Cognitive growth

“You cannot grow cognitively if you do not challenge yourself. For instance, reading a book outside the scope of your discipline can prove beneficial, because you get to be more knowledgeable. The advice I would give is that you must constantly remind yourself why you are here and let that be the driving force, even when things are gloomy, to let that motivate you. If you want to achieve certain things, you have to compromise and deprive yourself of other things; so, priorities should be the order of the day,” said the future Biology and English educator.

Looking back

Selloane is a proud product of Qwabi, Molibeli, and Reabetswe primary schools in Qwaqwa.

“I was born and bred here at Mandela Park in Qwaqwa. I did my Grades 10-12 at Moteka Secondary School, and that is why I would like to go back and teach at a public school – to bring about change in my community.”

Other awards Selloane received, were the Faculty of Education Overall Best Performer, and the Top Academic Achiever in the 2018/2019 SRC. Clearly, bosso ke Selloane!

Some of the recipients on the day were:
Dineo Tsotetsi (81,5%) – Faculty of Economic and Management Sciences Overall Best Achiever
Katleho Motloung (78, 3%) – Faculty of Natural and Agricultural Sciences Overall Best Achiever
Tina Magaqa (74%) – Faculty of the Humanities Overall Best Achiever
Pakiso Mthembu – Sportsman of the Year
Sandakahle Msamariya Khumalo – Sportswoman of the Year
Thabo Mdletshe – UFS101 Teaching Assistant of the Year
Charlotte Maxeke Residence – The Cleanest Residence on Campus
Siphamandla Shabangu – Selfless Volunteer and Gateway Mentor
UFS Qwaqwa Campus Chorale – Outstanding Performing Arts and Cultural Society 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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