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18 October 2019 | Story Valentino Ndaba | Photo Stephen Collett
Prof Nico Luwes
Paying tribute to staff members who have help build the Kovsie legacy such as Prof Nico Luwes.

Institutions are people. Staff members who keep universities going are the champions of education, be it in academic or support functions. This year’s Recognition of Service Awards honoured the commitment of 64 staff members to the University of the Free State (UFS). 

Prof Francis Petersen, Rector and Vice-Chancellor of the UFS, led the ceremony in which staff members who have served the institution for 25 years and longer received awards. “Thank you for your long service, loyalty, and steadfast support to the institution throughout its successes, developments, and challenges over the years,” he said at a dinner celebration held at the Bloemfontein Campus on 16 October 2019.

The recipients have contributed a combined total of 1 940 years to make Kovsies the transforming learning space it is today. “This means they have collectively been in service for 23 280 months and have collectively worked an average of 465 600 workdays,” said Prof Petersen, who also expressed gratitude to the 44 colleagues who are retiring this year. 

From a Kovsie student to serving for four decades

Prof Nico Luwes, Head of the Department of Drama and Theatre Arts, was also honoured for his 40 years of service along with six other staff members in that year category. 

He joined the university as a first-year student in 1974 and has been HOD from 1980. His family, including his parents, have collected a total of 21 degrees and diplomas from the university. 

For Prof Luwes, the adage “times flies when you are having fun” rings true. When asked what it means to receive the award, his response was: “It fills me with gratitude, thankfulness and joy. I realised that these years were filled with so many wonderful opportunities and challenges to grow as a lecturer, researcher, and theatre artist, that I did not even notice that time was flying by. What an honour to be associated with this wonderful institution – my beloved Kovsies!”

Planting the seeds and reaping the fruits

In addition to having the opportunity to write and direct various new plays and three musicals, Prof Luwes has had an impact on many lives. He managed to obtain over R8million in third-stream grants. These grants supported bursaries for drama students, academic internships, departmental and professional artistic theatre projects, and undertakings by the Free State Theatre Arts – the department’s professional group.

A token of appreciation

In light of both gradual and rapid changes seen in the higher-education sector, a committed and quality talent pool is a priceless asset. The university’s 115 years of a transforming existence owes much to staff members such as those who were honoured with the Recognition of Service Awards.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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