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09 October 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
SA animal population genetically more diverse than Europe
The Department of Genetics appointed the curator of the mammal collection in Austria’s Natural History Museum, Prof Frank Zachos. From the left are: Lerato Diseko, PhD Human Molecular Genetics; Prof Paul Grobler; Sivuyile Peni, MSc Molecular Genetics; Prof Frank Zachos; and Gerhard van Bosch, MSc Conservation Genetics.


South Africa is one of the greatest places on this planet to study mammals. These are the words of Prof Frank Zachos, newly appointed affiliated Professor in the Department of Genetics at the University of the Free State (UFS). 

He is also the curator of the Mammal Collection at the Natural History Museum in Vienna, Austria, the editor of the Elsevier journal Mammalian Biology, and author of several books, including Species Concepts in Biology. 

During a visit to South Africa, Prof Zachos addressed a group of UFS staff and students on the topic, ‘Conservation biology and genetics on two continents – case studies from mammalogy and ornithology’.

Inbreeding and deformities 

According to Prof Paul Grobler, Head of the UFS Department of Genetics, Prof Zachos has much experience in conservation biology studies. A large part of his work is on the population/conservation genetics of mammals (particularly deer) and, to a lesser degree, birds. Among others, he has studied red deer and the alpine golden eagle and has previously collaborated with Prof Grobler on projects involving local impala and gemsbok populations. 

Prof Grobler explains: “Typical conservation genetics studies helps one understand whether it's genetically going well with a species or population or not. This information can then be used to decide whether to move new animals to a population to prevent loss of genetic diversity.”

In his lecture, Prof Zachos explained the genetic diversity of red deer across Europe, and how this was influenced by past events (glaciers), but also by current anthropogenic factors (motor highways). 

He said there are several similarities between the mammals and birds of Europe and South Africa. The area south of the Sahara, however, is more of a biodiversity hotspot, unlike most areas in Europe where there is often lower genetic diversity in certain species. European deer species, for instance, are inherently less genetically diverse than antelope.

“Small population sizes can result in inbreeding. In some animals, this can result in deformities such as a shorter lower jaw or calves born without eyes,” said Prof Zachos.

Tracing geographic origin

With information on the gene diversity of a population of animals, authorities can implement preventative measures to address inbreeding, e.g. building green bridges to connect populations.

Population/conservation genetics studies are also helpful to determine which animals from a certain population are native to a specific area. Prof Zachos was involved in a study for the Belgian government, tracing the geographic and genetic origin of the country’s red deer. 

He said the ideal is to have genetic information for every population for management applications. 

During his visit, Prof Zachos also visited the Doornkloof Nature Reserve, since he is co-supervising a PhD student in the UFS Department of Genetics, who is based at Doornkloof. 

News Archive

UFS alumnus receives PhD in Statistics from the University of Oxford
2016-06-03

Description: DW Bester  Tags: DW Bester

In May of this year, DW Bester obtained
a DPhil in Statistics at the University of
Oxford.
Photo: Supplied

On 14 May this year, Dr DW Bester received a DPhil in Statistics from the University of Oxford. The entire ceremony, which was held in the Sheldonian Theatre in Oxford, was conducted in Latin, as has been the case for the past 800 years.

Dr Bester completed his undergraduate studies and his honours degree at the University of the Free State (UFS). “At first, I was only planning to study for a master’s degree, but was privileged to get an opportunity to do a PhD as well. I didn’t think twice!” he says.

Studies at the University of Oxford


Universities in England do not require a master’s degree for PhD studies. With the help of Prof Max Finkelstein from the UFS Department of Mathematical Statistics and Actuarial Science, Dr Bester registered for the DPhil programme in Statistics directly after his honours studies.

“The title of my thesis was: Joint survival models: A Bayesian investigation of longitudinal volatility. It dealt with a problem in the medical field to determine the cause of stroke risk: is it the absolute level of blood pressure, or the volatility thereof? The analysis of this question led to interesting models which needed advanced application techniques. I had to study these techniques and write programmes for their application.

Although Dr Bester is working currently as the technical head of a company that calculates insurance for power stations, satellites, rockets, and cyber risks, he would like to continue working with his Oxford supervisor in future to make the techniques they have developed more accessible for researchers outside of the field of statistics.
 
“Studying at Oxford requires hard work, perseverance, and a lot of luck. Luck plays a big role, since there are no guarantees that hard work will ensure you a spot in one of the top universities.

Regarding his studies at Oxford, Dr Bester thinks back on his exposure to the GNU/Linux operating system, and free software. “I have seen how valuable this is for analyses in practice. I also had the privilege of meeting the father of free software, Richard Stallman,” Dr Bester says.

2011 Rhodes Scholar

He was elected as Rhodes Scholar in 2011. According to Dr Bester, who has been interested in Mathematics since high school, the Rhodes scholarship was something of a fluke. He applied for the Rhodes scholarship on the recommendation of Prof Robert Schall of the Department of Mathematical Statistics and Actuarial Science.

Role of the UFS in his successes


In addition to the continued support from the team of passionate professors and lecturers at the UFS, the actuarial degree at the UFS is fraught with statistics. Emphasis is also placed on Bayesian statistics. This was crucial to his studies at Oxford. According to Dr Bester, this topic is emphasised strongly in the international statistics community.

Dr Bester regards the work done by two of his lecturers, Michael von Maltitz and Sean van der Merwe, among his highlights at the UFS. Since our first year, they have created an atmosphere of camaraderie among the students. “I think this contributed to the success of everybody. They also make an effort to present topics outside of the syllabus regularly,” says Bester.

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