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06 August 2020 | Story Leonie Bolleurs | Photo Charl Devenish
Poojah Jawallapersand strives for academic excellence and to empower others through research and innovation.

As South Africa commemorates Women’s Day on 9 August 2020 and continues Women’s Month celebrations throughout August, the UFS shines a spotlight on women who are making an impact on our three campuses on a daily basis.

One of these women is Poojah Jawallapersand, a PhD student majoring in Biochemistry. Poojah is part of the Pathogenic Yeast Research Group in the Department of Microbial, Biochemical and Food Biotechnology. 

In her current research study, she is investigating whether fungal yeast cells and components from the opportunistic and fungal pathogen Candida albicans can cause Alzheimer’s disease-like symptoms, and if these symptoms can be effectively treated through drug repositioning. The study is being conducted on zebrafish larvae.

Jawallapersand explains that drug repositioning is a drug development strategy that involves finding alternative indications for existing licensed drugs for novel therapeutic purposes. “In short, the use of old drugs for new uses. There is no cure for Alzheimer’s disease, hence this research will pave the way towards identifying effective treatment options to treat the disease,” she says. 

“Be confident and dare to be yourself because you are worth more than you think.” - Poojah Jawallapersand

An interview with Jawallapersand reveals more about the woman behind this much-needed research study. 

Is there a woman who inspires you and who you would like to celebrate this Women’s Month, and why?

“My mother and Mrs Deeya Domah (my high-school teacher) constantly inspire me and have played a pivotal role in my life. My mother taught me the value of life, encouraged me to embrace my cultural heritage and spirituality, and always urged me to be ‘original’.”

“As a teenager, Mrs Domah introduced me and made me fall in love with the study of life (biology), to the extent that I made a career out of it. She inspired me through her timeless elegance and passion for teaching and learning, her willingness to go the extra mile in helping her students, her role in environmental and ecological sustainability, her support towards the empowerment of women, and her influence as an educator and role model in the lives of numerous individuals.”

What are some challenges you have faced in your life that have made you a better woman?

“Although I have experienced several challenges in my life, the greatest challenge for me is still to master my mind and emotions. It is vital to have a strong support system to overcome these challenges; for me, this has always been my faith, my parents, and my sister. I am glad that I have gone through these trials; they taught me how to deal with some issues, to stay enthusiastic, to appreciate myself, to practice self-love, and to master the art of constantly picking myself up when I fall. I am still a work in progress and strive daily for self-improvement. However, I have become stronger, more resilient, and a better woman because of these challenges.”

What advice would you give to the 15-year-old you?

“Enjoy your adolescence, have fun, make memories, live these moments, and do not rush into adulthood. Stop trying to please other people and learn to say ‘no’. Be confident and dare to be yourself because you are worth more than you think.”

What would you say makes you a champion woman [of the UFS]?

“I am a champion woman of the UFS; I embrace my uniqueness, and I strive for academic excellence and to empower others through research and innovation. I say no to discrimination, no to gender-based violence, and no to gender inequality. I am generation equality, and this is my legacy.”

 

News Archive

Heart diseases a time bomb in Africa, says UFS expert
2010-05-17

 Prof. Francis Smit

There are a lot of cardiac problems in Africa. Sub-Saharan Africa is home to the largest population of rheumatic heart disease patients in the world and therefore hosts the largest rheumatic heart valve population in the world. They are more than one million, compared to 33 000 in the whole of the industrialised world, says Prof. Francis Smit, Head of the Department of Cardiothoracic Surgery at the Faculty of Health Sciences at the University of the Free State (UFS).

He delivered an inaugural lecture on the topic Cardiothoracic Surgery: Complex simplicity, or simple complexity?

“We are also sitting on a time bomb of ischemic heart disease with the WHO (World Health Organisation) estimating that CAD (coronary artery disease) will become the number-one killer in our region by 2020. HIV/Aids is expected to go down to number 7.”

Very little is done about it. There is neither a clear nor coordinated programme to address this expected epidemic and CAD is regarded as an expensive disease, confined to Caucasians in the industrialised world. “We are ignoring alarming statistics about incidences of adult obesity, diabetes and endemic hypertension in our black population and a rising incidence of coronary artery interventions and incidents in our indigenous population,” Prof. Smit says.

Outside South Africa – with 44 units – very few units (about seven) perform low volumes of basic cardiac surgery. The South African units at all academic institutions are under severe threat and about 70% of cardiac procedures are performed in the private sector.

He says the main challenge in Africa has become sustainability, which needs to be addressed through education. Cardiothoracic surgery must become part of everyday surgery in Africa through alternative education programmes. That will make this specialty relevant at all levels of healthcare and it must be involved in resource allocation to medicine in general and cardiothoracic surgery specifically.

The African surgeon should make the maximum impact at the lowest possible cost to as many people in a society as possible. “Our training in fields like intensive care and insight into pulmonology, gastroenterology and cardiology give us the possibility of expanding our roles in African medicine. We must also remember that we are trained physicians as well.

“Should people die or suffer tremendously while we can train a group of surgical specialists or retraining general surgeons to expand our impact on cardiothoracic disease in Africa using available technology maybe more creatively? We have made great progress in establishing an African School for Cardiothoracic Surgery.”

Prof. Smit also highlighted the role of the annual Hannes Meyer National Registrar Symposium that culminated in having an eight-strong international panel sponsored by the ICC of EACTS to present a scientific course as well as advanced surgical techniques in conjunction with the Hannes Meyer Symposium in 2010.

Prof. Smit says South Africa is fast becoming the driving force in cardiothoracic surgery in Africa. South Africa is the only country that has the knowledge, technology and skills base to act as the springboard for the development of cardiothoracic surgery in Africa.

South Africa, however, is experiencing its own problems. Mortality has doubled in the years from 1997 to 2005 and half the population in the Free State dies between 40 to 44 years of age.

“If we do not need health professionals to determine the quality and quantity of service delivery to the population and do not want to involve them in this process, we can get rid of them, but then the political leaders making that decision must accept responsibility for the clinical outcomes and life expectancies of their fellow citizens.

“We surely cannot expect to impose the same medical legal principles on professionals working in unsafe hospitals and who have complained and made authorities aware of these conditions than upon those working in functional institutions. Either fixes the institutions or indemnifies medical personnel working in these conditions and defends the decision publicly.

“Why do I have to choose the three out of four patients that cannot have a lifesaving operation and will have to die on their own while the system pretends to deliver treatment to all?”

Prof. Smit says developing a service package with guidelines in the public domain will go a long way towards addressing this issue. It is also about time that we have to admit that things are simply not the same. Standards are deteriorating and training outcomes are or will be affected.

The people who make decisions that affect healthcare service delivery and outcomes, the quality of training platforms and research, in a word, the future of South African medicine, firstly need rules and boundaries. He also suggested that maybe the government should develop health policy in the public domain and then outsource healthcare delivery to people who can actually deliver including thousands of experts employed but ignored by the State at present.

“It is time that we all have to accept our responsibilities at all levels… and act decisively on matters that will determine the quality and quantity of medical care for this and future generations in South Africa and Africa. Time is running out,” Prof. Smit says.
 

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