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28 September 2020 | Story Andre Damons | Photo Supplied
Dr Martin Nyaga, Senior Lecturer and Researcher: NGS, will be heading the World Health Organisation Collaborating Centre (WHO CC).
The University of the Free State (UFS) has been designated a World Health Organisation Collaborating Centre (WHO CC), and the university’s Next Generation Sequencing (NGS) Unit, in partnership with the World Health Organisation (WHO), will for the next four years be conducting genome sequencing of pathogenic organisms, including rotavirus strains from the African continent. 

This centre will be part of the Vaccine Preventable Diseases (VPD) Pathogens Genomics Cluster and will run from September 2020 to September 2024. 

Dr Martin Nyaga, Senior Lecturer and Researcher: NGS/Virology, who will be heading the WHO CC, says an institution is designated as a WHO CC by the WHO Director-General and endorsed by the host country’s minister of health to form part of an international collaborative network, carrying out activities in support of the WHO programmess at all levels. A designation as a WHO CC is a time-limited agreement of collaboration between WHO and the designated institution, through which the latter agrees to implement a series of concrete activities, specifically designed for WHO.

A supreme achievement

Says Dr Nyaga: “In my opinion, a WHO CC designation is one of the supreme achievements an institution can be conferred as a recognition for foregoing exceptional collaborative venture with the WHO and showing future potential to assist the WHO with its global programmes and in our case, the WHO Regional Office for Africa region to offer solutions to the WHO VPD Surveillance and pathogens genomics cluster.”

According to Dr Nyaga this designation was awarded to the UFS after the WHO was content with the outcome of a service contract whereby the UFS-NGS unit undertook a pilot rotavirus surveillance project at whole genome level, using two African countries for the pilot, Rwanda and Zambia.

“From the outcomes of the pilot surveillance project between 2017 and 2019, the WHO/AFRO was satisfied with the genomic data that was generated and partially disseminated in scientific databases and journals as a collaborative venture. 

“It was thus proposed to strengthen its existing collaboration with the UFS-NGS Unit, which initiated the application process to designate the UFS-NGS unit as a WHO CC, an initiative that has taken approximately 20 months to finalise through the different phases of the application and approvals for the designation,” explains Dr Nyaga.

The purpose of the WHO CC

The new WHO CC will upon request by the WHO, implement agreed work plans in a timely manner and to the highest possible standards of quality and must comply with the referred terms of reference and conditions. These include: 
• Conducting genome sequencing of pathogenic organisms causing VPD, including rotavirus strains collected as part of the routine VPD surveillance using NGS technology and analysis of the generated datasets using bioinformatics tools.

• Conducting molecular characterisation of specimens collected during outbreaks and public health emergencies as part of the support for monitoring, preparedness and response to VPD disease outbreaks in Africa.

• Provide technical guidance to WHO on strategies to improve laboratory molecular diagnostics, molecular typing and NGS of rotavirus diarrheal strains and other enteropathogens to detect novel and re-emerging strains. 

• Conduct validation of tools and new molecular diagnostics for detection and characterisation of unusual or rare VPD strains to guide studies and development of new vaccines for VPD.

• Organise capacity-building and training workshops on whole genome sequencing of priority VPD pathogenic organisms.

The impact of the WHO CC on the work of the UFS-NGS 

According to Dr Nyaga, the designation brings extra responsibilities to his work and to the activities of the UFS-NGS unit. “Such initiatives are very welcome to enhance the business aspects, research and academic activities of the UFS-NGS unit, as the benefits are quite holistic since the collaboration enhances co-ownership of data and offers opportunities to train postgraduate students and other scientists.

“It also expands the research infrastructure and most importantly contributes to policy for numerous African governments in important decisions such as vaccine implementation activities, from an informed point of view and managing public health needs that require rapid response like outbreaks that may lead to pandemics.” 
• The current WHO CC designations at South African Institutions of higher learning and research can be found at: 

News Archive

Renowned writer for Africa Day
2012-05-31

 

Attending the lecture were, from left: Dr Choice Makhetha, Vice-Rector: External Relations; Prof Kwandiwe Kondlo, Director of the Centre for Africa Studies;Prof. Ngugi wa Thiong'o; Prof Lucius Botes, Dean of the Faculty of the Humanities, and Prof Andre Keet, Director of the Institute for Reconciliation and Social Justice..
Photo: Stephen Collett
25 May 2012

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Lecture: THE BLACKNESS OF BLACK: Africa in the World Today

Audio of the lecture

Profile of Professor Ngugi wa Thiong'o (pdf format)

“Flowers are all different, yet no flower claims to be more of a flower than the other.” With these words Kenyan writer and one of the continent's most celebrated authors, Prof. Ngugi wa Thiong’o, delivered the tenth annual Africa Day Memorial lecture on 25 May 2012 in the University of the Free State's (UFS) Odeion Theatre on the Bloemfontein Campus. The lecture was hosted by the Centre for Africa Studies.

Long before Prof. wa Thiong’o was led inside the venue by a praise singer, chairs were filled and people were shown to an adjoining room to follow the lecture. Others, some on the university's Qwaqwa Campus, followed via live streaming.

In his speech titled the Blackness of Black: Africa in the world today, Prof. wa Thiong’o looked at the standing of Africa in the world today. He highlighted the plight of those of African descent who are judged “based on a negative profile of blackness”.

Prof. wa Thiong’o recalled a humiliating experience at a hotel in San Francisco in the United States, where a staff member questioned him being a guest of the hotel. He shared a similar experience in New Jersey, where he and his wife were thought to be recipients of welfare cheques. He said this was far deeper than overt racism.

“The certainty is based on a negative profile of blackness taken so much for granted as normal that it no longer creates a doubt.”

Prof. wa Thiong’o said the self certainty that black is negative is not confined to white perception of black only.

“The biggest sin, then, is not that certain groups of white people, and even the West as a whole, may have a negative view of blackness embedded in their psyche, the real sin is that the black bourgeoisie in Africa and the world should contribute to that negativity and even embrace it by becoming participants or shareholders in a multibillion industry built on black negativity.”

“Africa has to review the roots of the current imbalance of power: it started in the colonisation of the body. Africa has to reclaim the black body with all its blackness as the starting point in our plunge into and negotiations with the world.”

Prof. wa Thiong’o concluded by saying that Africa must rediscover and reconnect with Kwame Nkrumah’s dreams of a politically and economically united Africa.

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