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28 September 2020 | Story Andre Damons | Photo Supplied
Dr Martin Nyaga, Senior Lecturer and Researcher: NGS, will be heading the World Health Organisation Collaborating Centre (WHO CC).
The University of the Free State (UFS) has been designated a World Health Organisation Collaborating Centre (WHO CC), and the university’s Next Generation Sequencing (NGS) Unit, in partnership with the World Health Organisation (WHO), will for the next four years be conducting genome sequencing of pathogenic organisms, including rotavirus strains from the African continent. 

This centre will be part of the Vaccine Preventable Diseases (VPD) Pathogens Genomics Cluster and will run from September 2020 to September 2024. 

Dr Martin Nyaga, Senior Lecturer and Researcher: NGS/Virology, who will be heading the WHO CC, says an institution is designated as a WHO CC by the WHO Director-General and endorsed by the host country’s minister of health to form part of an international collaborative network, carrying out activities in support of the WHO programmess at all levels. A designation as a WHO CC is a time-limited agreement of collaboration between WHO and the designated institution, through which the latter agrees to implement a series of concrete activities, specifically designed for WHO.

A supreme achievement

Says Dr Nyaga: “In my opinion, a WHO CC designation is one of the supreme achievements an institution can be conferred as a recognition for foregoing exceptional collaborative venture with the WHO and showing future potential to assist the WHO with its global programmes and in our case, the WHO Regional Office for Africa region to offer solutions to the WHO VPD Surveillance and pathogens genomics cluster.”

According to Dr Nyaga this designation was awarded to the UFS after the WHO was content with the outcome of a service contract whereby the UFS-NGS unit undertook a pilot rotavirus surveillance project at whole genome level, using two African countries for the pilot, Rwanda and Zambia.

“From the outcomes of the pilot surveillance project between 2017 and 2019, the WHO/AFRO was satisfied with the genomic data that was generated and partially disseminated in scientific databases and journals as a collaborative venture. 

“It was thus proposed to strengthen its existing collaboration with the UFS-NGS Unit, which initiated the application process to designate the UFS-NGS unit as a WHO CC, an initiative that has taken approximately 20 months to finalise through the different phases of the application and approvals for the designation,” explains Dr Nyaga.

The purpose of the WHO CC

The new WHO CC will upon request by the WHO, implement agreed work plans in a timely manner and to the highest possible standards of quality and must comply with the referred terms of reference and conditions. These include: 
• Conducting genome sequencing of pathogenic organisms causing VPD, including rotavirus strains collected as part of the routine VPD surveillance using NGS technology and analysis of the generated datasets using bioinformatics tools.

• Conducting molecular characterisation of specimens collected during outbreaks and public health emergencies as part of the support for monitoring, preparedness and response to VPD disease outbreaks in Africa.

• Provide technical guidance to WHO on strategies to improve laboratory molecular diagnostics, molecular typing and NGS of rotavirus diarrheal strains and other enteropathogens to detect novel and re-emerging strains. 

• Conduct validation of tools and new molecular diagnostics for detection and characterisation of unusual or rare VPD strains to guide studies and development of new vaccines for VPD.

• Organise capacity-building and training workshops on whole genome sequencing of priority VPD pathogenic organisms.

The impact of the WHO CC on the work of the UFS-NGS 

According to Dr Nyaga, the designation brings extra responsibilities to his work and to the activities of the UFS-NGS unit. “Such initiatives are very welcome to enhance the business aspects, research and academic activities of the UFS-NGS unit, as the benefits are quite holistic since the collaboration enhances co-ownership of data and offers opportunities to train postgraduate students and other scientists.

“It also expands the research infrastructure and most importantly contributes to policy for numerous African governments in important decisions such as vaccine implementation activities, from an informed point of view and managing public health needs that require rapid response like outbreaks that may lead to pandemics.” 
• The current WHO CC designations at South African Institutions of higher learning and research can be found at: 

News Archive

Maestros from the world stage now lecture at the Odeion School of Music
2014-02-19

 
Prof Ruth Goveia

 
Danré Strydom

 
George Foster

The Odeion School of Music (OSM) at the University of the Free State (UFS) recently endorsed its commitment to excellence with the appointment of three exceptional performing artists and lecturers.

Prof Ruth Goveia (piano), Danré Strydom (clarinet and saxophone) and George Foster (brass instruments) all hold international qualifications. In addition, all of them have received tutelage from world-renowned mentors and performed across the globe. Their respective CVs are awe-inspiring – to say the least.

Prof Goveia has been appointed as an associate professor at our university. She obtained her doctorate in Music in Piano from the Jacobs School of Music at the Indiana University, USA, after completing her master’s degree at the University of Cincinnati. Prof Goveia has gained immeasurable experience while holding positions at several prestigious institutions, including the Albion College in Michigan and the Indiana University.

As a soloist, Prof Goveia’s performances are staggering. She has appeared in a number of recitals across America and even performed as a guest artist at the Kalamazoo College of Music. She took part in the Chamber Music Project of the New York-based Artur Balsam Foundation, and collaborated with clarinetist Randall Paul on a duo tour of Georgia and Alabama.

Danré Strydom has been appointed as a junior lecturer in clarinet and saxophone. She will also co-ordinate the woodwind programme at the OSM. Her training began in Windhoek, Namibia, and continued on to the prestigious Jacobs School of Music in Indiana, USA. From there she joined the Ghent Conservatoire in Belgium, reading for two master’s degrees – completing both cum laude. Strydom has performed with several renowned orchestras ranging from the Vlaams Brabant Symphony (Belgium) to the Sinfonietta Breda (Netherlands).

George Foster is filling the position of a junior lecturer in brass instruments. He completed his BMus degree at the South African College of Music at the University of Cape Town where he received the Anton Rupert Merit prize. As former Fulbright scholar, Foster read for a master’s degree in Music at the University of North Texas. During his study period in the USA he was a member of the University of North Texas Wind Band, the Symphony Orchestra and the Chamber Orchestra. Here, he gained invaluable experience as a conductor as well.

Strydom and Foster are performing their duties at the Free State Symphony Orchestra (FSSO), as well as the OSM. They will both play an integral role as musicians and collaborators within the activities and initiatives of the FSSO, and serve as coaches and instructors for the Free State Youth Orchestra.

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