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28 September 2020 | Story Andre Damons | Photo Supplied
Dr Martin Nyaga, Senior Lecturer and Researcher: NGS, will be heading the World Health Organisation Collaborating Centre (WHO CC).

The University of the Free State (UFS) has been designated a World Health Organisation Collaborating Centre (WHO CC), and the university’s Next Generation Sequencing (NGS) Unit, in partnership with the World Health Organisation (WHO), will for the next four years be conducting genome sequencing of pathogenic organisms, including rotavirus strains from the African continent. 

This centre will be part of the Vaccine Preventable Diseases (VPD) Pathogens Genomics Cluster and will run from September 2020 to September 2024. 

Dr Martin Nyaga, Senior Lecturer and Researcher: NGS/Virology, who will be heading the WHO CC, says an institution is designated as a WHO CC by the WHO Director-General and endorsed by the host country’s minister of health to form part of an international collaborative network, carrying out activities in support of the WHO programmess at all levels. A designation as a WHO CC is a time-limited agreement of collaboration between WHO and the designated institution, through which the latter agrees to implement a series of concrete activities, specifically designed for WHO.

A supreme achievement

Says Dr Nyaga: “In my opinion, a WHO CC designation is one of the supreme achievements an institution can be conferred as a recognition for foregoing exceptional collaborative venture with the WHO and showing future potential to assist the WHO with its global programmes and in our case, the WHO Regional Office for Africa region to offer solutions to the WHO VPD Surveillance and pathogens genomics cluster.”

According to Dr Nyaga this designation was awarded to the UFS after the WHO was content with the outcome of a service contract whereby the UFS-NGS unit undertook a pilot rotavirus surveillance project at whole genome level, using two African countries for the pilot, Rwanda and Zambia.

“From the outcomes of the pilot surveillance project between 2017 and 2019, the WHO/AFRO was satisfied with the genomic data that was generated and partially disseminated in scientific databases and journals as a collaborative venture. 

“It was thus proposed to strengthen its existing collaboration with the UFS-NGS Unit, which initiated the application process to designate the UFS-NGS unit as a WHO CC, an initiative that has taken approximately 20 months to finalise through the different phases of the application and approvals for the designation,” explains Dr Nyaga.

The purpose of the WHO CC

The new WHO CC will upon request by the WHO, implement agreed work plans in a timely manner and to the highest possible standards of quality and must comply with the referred terms of reference and conditions. These include: 
• Conducting genome sequencing of pathogenic organisms causing VPD, including rotavirus strains collected as part of the routine VPD surveillance using NGS technology and analysis of the generated datasets using bioinformatics tools.

• Conducting molecular characterisation of specimens collected during outbreaks and public health emergencies as part of the support for monitoring, preparedness and response to VPD disease outbreaks in Africa.

• Provide technical guidance to WHO on strategies to improve laboratory molecular diagnostics, molecular typing and NGS of rotavirus diarrheal strains and other enteropathogens to detect novel and re-emerging strains. 

• Conduct validation of tools and new molecular diagnostics for detection and characterisation of unusual or rare VPD strains to guide studies and development of new vaccines for VPD.

• Organise capacity-building and training workshops on whole genome sequencing of priority VPD pathogenic organisms.

The impact of the WHO CC on the work of the UFS-NGS 

According to Dr Nyaga, the designation brings extra responsibilities to his work and to the activities of the UFS-NGS unit. “Such initiatives are very welcome to enhance the business aspects, research and academic activities of the UFS-NGS unit, as the benefits are quite holistic since the collaboration enhances co-ownership of data and offers opportunities to train postgraduate students and other scientists.

“It also expands the research infrastructure and most importantly contributes to policy for numerous African governments in important decisions such as vaccine implementation activities, from an informed point of view and managing public health needs that require rapid response like outbreaks that may lead to pandemics.” 
• The current WHO CC designations at South African Institutions of higher learning and research can be found at: 

News Archive

The UFS #FaceOfFacebook
2014-11-14

At the UFS, we are committed to our Human Project, which sets the standard for good behaviour and care. It reaches internally to our students and externally to our prospective students and our communities.

And so, the Kovsies #FaceOfFacebook was born from the need to communicate with students and thus become a virtual friend. Yearly auditions are held to choose the new face representing the UFS on Facebook. The successful candidate holds the title #FaceOfFacebook for the next 12 months, attending events and filming short video clips to post on our Facebook page.

We had a quick chat with our current #FaceOfFacebook, Katleho 'Blue' Letube …

Who is Blue?

"Media mistress, fashion phenom, diva divine darling, superwoman and lover of life.
I was born in a small town called Bothaville, where my mom and her side of the family are living . I started pre-school there, moved and completed my schooling career at St. Andrew's High School (a very proud S aint) in Welkom. That is where my dad and his side of the family are living . Also, I am a proud resident of House NJ vd Merwe and I am studying Governance and Political Transformation."

How do you balance everything you do?

"It's relatively easy for me to strike a balance between my academics, social life and leadership duties, because Jesus is at the centre of all that I do. He is my guide and my strength. However, I also take it upon myself to prioritise. Although I am a '' liker of things'' , I ensure that my academics are the priority and everything else falls into place perfectly."

Are you dating someone?

"Hahaha, wouldn't you just love to know? Well, yes I am off-market. I'm completely taken and I'm happy."

What drives you?

"I always feel the urge to expand myself by working harder, smarter, stronger, and more efficiently. If there's an extra mile to go, the strength inside me draws out the willingness and ability to go that extra mile."

What is it like being the #FaceOfFacebook?

"I have been privileged to be entrusted with this duty and I carry it out with pride and passion. Being the #FaceOfFacebook means you get to meet a new face on campus almost every day, because people recognis e you and want to know you better. This opportunity has opened many doors for me and has equipped me with skills that have allowed me to grow as an individual. Therefore I will forever be grateful."

Where are you going to be in five years from now?

"Five years from now I would like to see myself as a better person both personally and professionally, in a respectable and reputed position earned through my hard work and skills. However, do not be surprised if you see me as a presenter on Vuzu.TV."

Advice to prospective students?

"Do not be that pupil who enrolled at this awesome institute and never takes advantage of its kindness. The University of The Free State is an institution that offers an excessive amount of opportunities to students. Step up and get out of your comfort zone. See an opportunity, seek the opportunity and cease it. You are at a university that provides you with a platform for you to grow."

What's your favourite colour?

My favourite colours are Black, White and Blue – hahaha!!

Kovsies can keep in touch:

Facebook: Katlego Blue Letube
Twitter: @Princess_blue31
Instagram: katlegoletube

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