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02 September 2020 | Story Andre Damons | Photo Supplied
Dr Satyajit Tripathy
Dr Satyajit Tripathy, a postdoctoral fellow from the Department of Pharmacology and Physiology, won the medal for the best oral performance at a UNESCO/UNITWIN network web seminar attended by more than 300 people from various institutions around the world.

A postdoctoral fellow in Pharmacology at the University of the Free State (UFS) was awarded a medal for the best oral e-poster presentation (Postdoctoral Fellow category) at a UNESCO/UNITWIN Network web seminar.

The two-day webinar with the theme Current concepts of Environmental Pollution by Electromagnetic field and Coronavirus was held in early August and was attended by more than 300 delegates from approximately 30 institutions from different countries.

Dr Satyajit Tripathy from the Department of Pharmacology won the medal for his outstanding research presentation on Employment of old options to control novel Coronavirus: Pros and Cons (authors: Barsha Dassarma, Satyajit Tripathy, MG Matsabisa). His presentations looked at immunotherapeutic techniques, such as the convalescent plasma (CP) therapy and possible diverse modes of action of the antimalarial drug hydroxychloroquine (HCQ) against COVID-19 infection.

The award will serve as motivation

He was excited to hear that he had won the award, says Dr Tripathy.

“I never thought I would win, but I tried my best. On the topic of possible modes of action of HCQ against the viral infection, we have published in the ‘International Journal of Antimicrobial Agents’ (S Tripathy, B Dassarma, H Chabalala, S Roy, and MG Matsabisa / International Journal of Antimicrobial Agents 56 (2020) 106028). All the authors are grateful to Prof Glen Taylor, Research Director at the UFS, and the UFS Department of Pharmacology, for giving us the opportunity,” says Dr Tripathy. 
According to him, receiving this award is a validation and boost to his confidence. “I am thankful to Prof Motlalepula Matsabisa (supervisor) and Dr Barsha Dassarma (my wife), who are also contributing actively to this project. Moreover, the award is a symbol of respect for my work and the acceptance of a greater responsibility to keep the UFS flag flying high.”
Dr Tripathy goes further to say that it will motivate him to work on HCQ or nano-HCQ delivery research on Coronaviruses. In his doctoral study, it has been found that chitosan-based nanochloroquine delivery increases antimalarial efficacy against rodent parasites. Against the Coronavirus, this type of approach might work to reduce the dose and increase the efficacy of HCQ, explains Dr Tripathy. 

Immediate saviour from the pandemic

In his presentation, Dr Tripathy argues that while the world is finding expedited approvals for the development of vaccines that are time-dependent, preventative, and possibly not a cure, physicians are considering the convalescent plasma (CP) therapy as an immediate saviour, and the antimalarial drug hydroxychloroquine (HCQ) as therapeutic options against COVID-19 infection, after assessing results from larger prospective, randomised, dose-determining controlled clinical trials. 
He concludes that, “Overall, in this situation of unavailability of specific medication, the CP therapy and HCQ treatment might act as an immediate saviour for society from the pandemic.”

News Archive

Wildlife researcher in ground-breaking global research on giraffes
2017-10-20

Description: Giraffe read more Tags: giraffe, conservation, Dr Francois Deacon, Last of the Long Necks, Catching Giants 

Dr Deacon from the Department of Animal, Wildlife and Grassland
Sciences at the University of the Free State (UFS),
lead a multispecialist research group to catch
and collar giraffe to collect data that will
contribute to the conservation of these animals.
Photo: Prof Nico Smith


Capturing 51 giraffes without any injuries or mortalities to collect data that will contribute to the conservation of these animals is not for everyone. Capturing a giraffe with minimum risk to the animal and the people involved, requires extraordinary skill, planning, and teamwork. “This exercise is a dangerous task, since a well-placed kick from these large and extremely powerful animals can cause serious injuries. Early in October was the first time that giraffes were captured on such a large scale,” said wildlife researcher Dr Francois Deacon.
 
Dr Deacon from the Department of Animal, Wildlife and Grassland Sciences at the University of the Free State (UFS), led a multispecialist research group of over 30 people from 10 different countries to collect information about these little-known animals.

UFS first to collar giraffe
Taking a global approach, the team responsible for this intricate process consisted of wildlife biologists, conservationists, interdisciplinary scientists and five specialist veterinarians who are experienced in catching and working with wild animals. Specialised drugs sponsored by Dr Kobus Raath from Wildlife Pharmaceuticals, tested for the first time and administered with a dart gun were used to tranquillise the giraffe, which then allowed for the GPS collars to be fitted.  These collars, sponsored by Africa Wildlife Tracking, enable the researchers to record the location of individual giraffe for up to two years, give 24/7 readings, irrespective of weather conditions. In this cost-effective manner, data can be gathered on climatic factors, giraffe communication, social behaviour, home ranges, seasonal movements, human and giraffe interaction zones, as well as migration routes and the duration of the migration process. The collars will effectively be used to locate individuals to collect faecal samples for hormonal cycles, stress hormones, nutrient deficiencies based on diet and also internal parasites. 

“This knowledge we gain is the key to all keys in saving this iconic animal from becoming extinct,” said Dr Deacon.

Six years ago, during a pilot study, Dr Deacon was the first researcher to fit giraffes with a GPS collar. Collaring is less invasive and allows researchers to collect detailed samples. Not only was extensive knowledge and experience gained during the process, but he also initiated interest from the filmmaker and conservationist, Ashley Scott Davison, executive producer of Iniosante Inc. 

Getting to tell the story

Davison, who was doing research for a film on giraffe learnt about the silent extinction of the species. In a great number of countries giraffe numbers have been declining by as much as 40% over only a few years since 2000. Today West Africa has between 400 to 600 giraffe left while four out of five giraffes were lost in East Africa since 2000. This is a considerable decline in numbers and poses a real threat to the survival of the species in the longer term. At the end of 2016, the giraffe was classified as vulnerable on the International Union for Conservation of Nature Red Data list.

According to Davison, children in school learn about the destruction caused by ivory poaching and habitat loss. But in Africa today, there are six times as many elephants as there are giraffes. 

In the process to find out more about this majestic species Davison learnt of Dr Deacon’s work. After being introduced to and spending time with Dr Deacon, Davison not only describes the UFS as the leader in the conservation of giraffes but he returned to the university, three times to help build a dedicated research team to address unanswered research questions within various disciplines.

Flowing from the affiliation with the UFS is Iniosante’s award-winning production of a documentary, “Last of the Longnecks”. The film has received several awards, including official selection at the 2017 Global Peace Film Festival, the Wildlife Conservation Film Festival and the Environmental Film Festival in the US capital. 

The film team accompanied the multispecialist research team last week to gather footage for a follow-up documentary, “Catching Giants”. This film is expected to air in middle 2018.

 Video clip of the event: https://www.dropbox.com/s/d3kv9we690bwwto/giraffe_UFS_revision-01a.mp4?dl=0

Video clip of the event: RooistoelTV

Former articles on this topic:

18 Nov 2016: http://www.ufs.ac.za/templates/news-archive-item?news=7964 
23 August 2016: http://www.ufs.ac.za/templates/news-archive-item?news=7856 
9 March 2016:Giraffe research broadcast on National Geographic channel
18 Sept 2015 Researchers reach out across continents in giraffe research
29 May 2015: Researchers international leaders in satellite tracking in the wildlife environment

 

 

 

 

 

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