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02 September 2020 | Story Andre Damons | Photo Supplied
Dr Satyajit Tripathy
Dr Satyajit Tripathy, a postdoctoral fellow from the Department of Pharmacology and Physiology, won the medal for the best oral performance at a UNESCO/UNITWIN network web seminar attended by more than 300 people from various institutions around the world.

A postdoctoral fellow in Pharmacology at the University of the Free State (UFS) was awarded a medal for the best oral e-poster presentation (Postdoctoral Fellow category) at a UNESCO/UNITWIN Network web seminar.

The two-day webinar with the theme Current concepts of Environmental Pollution by Electromagnetic field and Coronavirus was held in early August and was attended by more than 300 delegates from approximately 30 institutions from different countries.

Dr Satyajit Tripathy from the Department of Pharmacology won the medal for his outstanding research presentation on Employment of old options to control novel Coronavirus: Pros and Cons (authors: Barsha Dassarma, Satyajit Tripathy, MG Matsabisa). His presentations looked at immunotherapeutic techniques, such as the convalescent plasma (CP) therapy and possible diverse modes of action of the antimalarial drug hydroxychloroquine (HCQ) against COVID-19 infection.

The award will serve as motivation

He was excited to hear that he had won the award, says Dr Tripathy.

“I never thought I would win, but I tried my best. On the topic of possible modes of action of HCQ against the viral infection, we have published in the ‘International Journal of Antimicrobial Agents’ (S Tripathy, B Dassarma, H Chabalala, S Roy, and MG Matsabisa / International Journal of Antimicrobial Agents 56 (2020) 106028). All the authors are grateful to Prof Glen Taylor, Research Director at the UFS, and the UFS Department of Pharmacology, for giving us the opportunity,” says Dr Tripathy. 
According to him, receiving this award is a validation and boost to his confidence. “I am thankful to Prof Motlalepula Matsabisa (supervisor) and Dr Barsha Dassarma (my wife), who are also contributing actively to this project. Moreover, the award is a symbol of respect for my work and the acceptance of a greater responsibility to keep the UFS flag flying high.”
Dr Tripathy goes further to say that it will motivate him to work on HCQ or nano-HCQ delivery research on Coronaviruses. In his doctoral study, it has been found that chitosan-based nanochloroquine delivery increases antimalarial efficacy against rodent parasites. Against the Coronavirus, this type of approach might work to reduce the dose and increase the efficacy of HCQ, explains Dr Tripathy. 

Immediate saviour from the pandemic

In his presentation, Dr Tripathy argues that while the world is finding expedited approvals for the development of vaccines that are time-dependent, preventative, and possibly not a cure, physicians are considering the convalescent plasma (CP) therapy as an immediate saviour, and the antimalarial drug hydroxychloroquine (HCQ) as therapeutic options against COVID-19 infection, after assessing results from larger prospective, randomised, dose-determining controlled clinical trials. 
He concludes that, “Overall, in this situation of unavailability of specific medication, the CP therapy and HCQ treatment might act as an immediate saviour for society from the pandemic.”

News Archive

Professor’s research part of major global programme
2011-04-04

 

Prof. Zakkie Pretorius, professor in Plant Pathology in the Department of Plant Sciences at our university

Research by Zakkie Pretorius, professor in Plant Pathology in the Department of Plant Sciences at our university, has become part of Phase II of a mayor global project to combat deadly strains of a wheat pathogen that poses a threat to global food security.

Prof. Pretorius focuses on the identification of resistance in wheat to the stem rust disease and will assist breeders and geneticists in the accurate phenotyping of international breeding lines and mapping populations. In addition, Prof. Pretorius will support scientists from Africa with critical skills development through training programmes. During Phase I, which ends in 2011, he was involved in pathogen surveillance in Southern Africa and South Asia.
 
The Department of International Development (DFID) in the United Kingdom and the Bill and Melinda Gates Foundation will invest $40 million over the next five years in the global project led by the Cornell University. The project is aimed at combating deadly strains of Ug99, an evolving wheat pathogen that is a dangerous threat to global food security, especially in the poorest nations. 
 
The Cornell University said in a statement, the grant made to the Durable Rust Resistance in Wheat (DRRW) project at Cornell will support efforts to identify new stem-rust resistant genes in wheat, improve surveillance, and multiply and distribute rust-resistant wheat seed to farmers and their families.
 
Researchers worldwide will be able to play an increasingly vital role in protecting wheat fields from dangerous new forms of stem rust, particularly in countries whose people can ill afford the economic impact of damage to this vital crop.
 
The Ug99 strain was discovered in Kenya in 1998, but are now also threatening major wheat-growing areas of Southern and Eastern Africa, the Central Asian Republics, the Caucasus, the Indian subcontinent, South America, Australia and North America.
 
Prof. Pretorius was responsible for the first description of this strain in 1999.
 
Among Cornell’s partners are national research centres in Kenya and Ethiopia, and scientists at two international agricultural research centres that focus on wheat, the Mexico-based International Maize and Wheat Improvement Center (known by its Spanish acronym as CIMMYT), and the International Center  for Agricultural Research in the Dry Areas (ICARDA), in Syria. Advanced research laboratories in the United States, Canada, China, Australia, Denmark and South Africa also collaborate on the project. The DRRW project now involves more than 20 leading universities and research institutes throughout the world, and scientists and farmers from more than 40 countries.


Media Release
28 March 2011
Issued by: Lacea Loader
Director: Strategic Communication
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: news@ufs.ac.za

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