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02 September 2020 | Story Andre Damons | Photo Supplied
Dr Satyajit Tripathy
Dr Satyajit Tripathy, a postdoctoral fellow from the Department of Pharmacology and Physiology, won the medal for the best oral performance at a UNESCO/UNITWIN network web seminar attended by more than 300 people from various institutions around the world.

A postdoctoral fellow in Pharmacology at the University of the Free State (UFS) was awarded a medal for the best oral e-poster presentation (Postdoctoral Fellow category) at a UNESCO/UNITWIN Network web seminar.

The two-day webinar with the theme Current concepts of Environmental Pollution by Electromagnetic field and Coronavirus was held in early August and was attended by more than 300 delegates from approximately 30 institutions from different countries.

Dr Satyajit Tripathy from the Department of Pharmacology won the medal for his outstanding research presentation on Employment of old options to control novel Coronavirus: Pros and Cons (authors: Barsha Dassarma, Satyajit Tripathy, MG Matsabisa). His presentations looked at immunotherapeutic techniques, such as the convalescent plasma (CP) therapy and possible diverse modes of action of the antimalarial drug hydroxychloroquine (HCQ) against COVID-19 infection.

The award will serve as motivation

He was excited to hear that he had won the award, says Dr Tripathy.

“I never thought I would win, but I tried my best. On the topic of possible modes of action of HCQ against the viral infection, we have published in the ‘International Journal of Antimicrobial Agents’ (S Tripathy, B Dassarma, H Chabalala, S Roy, and MG Matsabisa / International Journal of Antimicrobial Agents 56 (2020) 106028). All the authors are grateful to Prof Glen Taylor, Research Director at the UFS, and the UFS Department of Pharmacology, for giving us the opportunity,” says Dr Tripathy. 
According to him, receiving this award is a validation and boost to his confidence. “I am thankful to Prof Motlalepula Matsabisa (supervisor) and Dr Barsha Dassarma (my wife), who are also contributing actively to this project. Moreover, the award is a symbol of respect for my work and the acceptance of a greater responsibility to keep the UFS flag flying high.”
Dr Tripathy goes further to say that it will motivate him to work on HCQ or nano-HCQ delivery research on Coronaviruses. In his doctoral study, it has been found that chitosan-based nanochloroquine delivery increases antimalarial efficacy against rodent parasites. Against the Coronavirus, this type of approach might work to reduce the dose and increase the efficacy of HCQ, explains Dr Tripathy. 

Immediate saviour from the pandemic

In his presentation, Dr Tripathy argues that while the world is finding expedited approvals for the development of vaccines that are time-dependent, preventative, and possibly not a cure, physicians are considering the convalescent plasma (CP) therapy as an immediate saviour, and the antimalarial drug hydroxychloroquine (HCQ) as therapeutic options against COVID-19 infection, after assessing results from larger prospective, randomised, dose-determining controlled clinical trials. 
He concludes that, “Overall, in this situation of unavailability of specific medication, the CP therapy and HCQ treatment might act as an immediate saviour for society from the pandemic.”

News Archive

A model of resilience – Dr Anja Botha probes into the ability to recover from trauma
2014-12-02

She may have been awarded her doctorate degree only in July 2014, but Psychology lecturer at the University of the Free State (UFS), Dr Anja Botha, is already making a name for herself with her latest research.

Her study aims to develop a model of resilience for South African adolescents exposed to trauma. “The broad field, within which I work, is that of Developmental Psychology, with a specific focus on child and adolescent development and therapy,” says Dr Botha. 

Resilience studies are situated within Developmental Psychology since normal developmental tasks – such as achieving self-confidence and building supportive relationships – contribute greatly to children’s resilience. Resilience broadly refers to the individual’s ability to ‘bounce back’ after being exposed to adversity.

“The model of resilience which I compiled was a good fit for my participant group, indicating that the model explains the development of resilience in these adolescents well. The factors that I found to promote resilience in the South African context include various coping skills, intra- and interpersonal strengths, family involvement, and school engagement.

“Thus, aside from my passion for resilience studies, I am also very much interested in coping, strength-based interventions, parental guidance and school-based programmes.”

Dr Botha was awarded a Donald J Cohen fellowship in August 2014 during the 21st World Congress of the International Association for Child and Adolescent Psychiatrists and Allied Professions. The fellowship is in recognition of her work as an emerging international scholar in the field of child and adolescent mental health. This award was based on both her research as well as her involvement in the training of postgraduate students in child psychology.

She is currently supervising a number of master’s students’ research on various constructs related to resilience.

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