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02 September 2020 | Story Andre Damons | Photo Supplied
Dr Satyajit Tripathy
Dr Satyajit Tripathy, a postdoctoral fellow from the Department of Pharmacology and Physiology, won the medal for the best oral performance at a UNESCO/UNITWIN network web seminar attended by more than 300 people from various institutions around the world.

A postdoctoral fellow in Pharmacology at the University of the Free State (UFS) was awarded a medal for the best oral e-poster presentation (Postdoctoral Fellow category) at a UNESCO/UNITWIN Network web seminar.

The two-day webinar with the theme Current concepts of Environmental Pollution by Electromagnetic field and Coronavirus was held in early August and was attended by more than 300 delegates from approximately 30 institutions from different countries.

Dr Satyajit Tripathy from the Department of Pharmacology won the medal for his outstanding research presentation on Employment of old options to control novel Coronavirus: Pros and Cons (authors: Barsha Dassarma, Satyajit Tripathy, MG Matsabisa). His presentations looked at immunotherapeutic techniques, such as the convalescent plasma (CP) therapy and possible diverse modes of action of the antimalarial drug hydroxychloroquine (HCQ) against COVID-19 infection.

The award will serve as motivation

He was excited to hear that he had won the award, says Dr Tripathy.

“I never thought I would win, but I tried my best. On the topic of possible modes of action of HCQ against the viral infection, we have published in the ‘International Journal of Antimicrobial Agents’ (S Tripathy, B Dassarma, H Chabalala, S Roy, and MG Matsabisa / International Journal of Antimicrobial Agents 56 (2020) 106028). All the authors are grateful to Prof Glen Taylor, Research Director at the UFS, and the UFS Department of Pharmacology, for giving us the opportunity,” says Dr Tripathy. 
According to him, receiving this award is a validation and boost to his confidence. “I am thankful to Prof Motlalepula Matsabisa (supervisor) and Dr Barsha Dassarma (my wife), who are also contributing actively to this project. Moreover, the award is a symbol of respect for my work and the acceptance of a greater responsibility to keep the UFS flag flying high.”
Dr Tripathy goes further to say that it will motivate him to work on HCQ or nano-HCQ delivery research on Coronaviruses. In his doctoral study, it has been found that chitosan-based nanochloroquine delivery increases antimalarial efficacy against rodent parasites. Against the Coronavirus, this type of approach might work to reduce the dose and increase the efficacy of HCQ, explains Dr Tripathy. 

Immediate saviour from the pandemic

In his presentation, Dr Tripathy argues that while the world is finding expedited approvals for the development of vaccines that are time-dependent, preventative, and possibly not a cure, physicians are considering the convalescent plasma (CP) therapy as an immediate saviour, and the antimalarial drug hydroxychloroquine (HCQ) as therapeutic options against COVID-19 infection, after assessing results from larger prospective, randomised, dose-determining controlled clinical trials. 
He concludes that, “Overall, in this situation of unavailability of specific medication, the CP therapy and HCQ treatment might act as an immediate saviour for society from the pandemic.”

News Archive

UFS lecturer overcomes barriers to become world-class researcher
2016-09-05

Description: Dr Magteld Smith researcher and deaf awareness activist Tags: Dr Magteld Smith researcher and deaf awareness activist

Dr Magteld Smith researcher and deaf awareness
activist, from the Department of Otorhinolaryngology
at the UFS.
Photo: Nonsindiso Qwabe

Renowned author and disability activist Helen Keller once said the problems that come with being deaf are deeper and more far-reaching than any other physical disability, as it means the loss of the human body’s most vital organ, sound.

Dr Magteld Smith, researcher at the Department of Otorhinolaryngology (Ear, Nose and Throat) at the University of the Free State, said hearing loss of any degree can have psychological and sociological implications which may impair the day-to-day functioning of an individual, as well as preventing the person from reaching full potential. That is why Smith is making it her mission to bring about change in the stigmatisation surrounding deafness.

Beating the odds
Smith was born with bilateral (both ears) severe hearing loss, which escalated to profound deafness. But she has never allowed it to hinder her quality of life. She matriculated from a school for the deaf in 1985. In 2008 she received a cochlear implant   a device that replaces the functioning of the damaged inner ear by providing a sense of sound to the deaf person   which she believes transformed her life. Today, she is the first deaf South African to possess two masters degrees and a PhD.

She is able to communicate using spoken language in combination with her cochlear implant, lip-reading and facial expressions. She is also the first and only deaf person in the world to have beaten the odds to become an expert researcher in various fields of deafness and hearing loss, working in an Otorhinolaryngology department.

Advocating for a greater quality of life
An advocate for persons with deafness, Smith conducted research together with other experts around the world which illustrated that cochlear implantation and deaf education were cost-effective in Sub-Saharan Africa. The cost-effectiveness of paediatric cochlear implantation has been well-established in developed countries; but is unknown in low resource settings.

However, with severe-to-profound hearing loss five times higher in low and middle-income countries, the research emphasises the need for the development of cost-effective management strategies in these settings.

This research is one of a kind in that it states the quality of life and academic achievements people born with deafness have when they use spoken language and sign language as a mode of communication is far greater than those who only use sign language without any lip-reading.

Deafness is not the end

What drives Smith is the knowledge that deaf culture is broad and wide. People with disabilities have their own talents and skills. All they need is the support to steer them in the right direction. She believes that with the technological advancements that have been made in the world, deaf people also have what it takes to be self-sufficient world-changers and make a lasting contribution to humanity.

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