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20 April 2021 | Story Cornelius Hagenmeier

On 25 May 2021, Africa will celebrate the 58th anniversary of the founding of the Organisation of African Unity (OAU). A central tenet of the organisation, which was the predecessor of the African Union (AU), is African solidarity. This call celebrates the idea and the ideal of African solidarity. As we are preparing for Africa Month 2021, we received the shocking news about the damage to the University of Cape Town’s African Studies collection. The need for African solidarity to mitigate this immense loss has inspired the theme of the 2021 UFS virtual Africa Month celebration, ‘solidarity in knowledge production and recording’.

From the establishment of the OAU and with the later formation of the AU, member states undertook to coordinate and intensify their cooperation and efforts to achieve a better life for the people of Africa.

Africa Day Memorial Lecture

The UFS has a long tradition of commemorating Africa Day and the ideas underpinning it. Every year, diverse events aimed at advancing African unity and solidarity take place during Africa Month –traditionally, the highlight is the Africa Day Memorial Lecture hosted by the University's Centre for Gender and Africa Studies. On 19 May 2021 at 19:00 (SAST), Prof Walter D Mignolo, a guru of decoloniality, will virtually deliver this year’s lecture titled The beauty of the sovereign people: Jean Casimir and the Decolonial History of Haiti, to honour the memory of transatlantic slavery by reflecting on former ambassador, Prof Jean Casimir, who has shifted the geography of reasoning by breaking the code of the standard history of the slave trade, the African diaspora in the Caribbean, and of captive human beings in the plantations. The discussant will be CGAS Extraordinary Professor and Professor of Epistemologies of the Global South at the University of Bayreuth, Prof Sabelo J Ndlovu-Gatsheni.  

As COVID-19 continues to ravage the world, Africans have been fighting against the pandemic in various ways and have achieved considerable success in this regard. Given the economic and social challenges associated with the pandemic, fostering African solidarity and further developing the underpinning philosophy of ubuntu appear to be particularly worthwhile projects.

A virtual celebration of Africa Month

The UFS 2021 Africa Month commemorations will again take a virtual format. It will include a focus on UFS engagement on the continent, partnerships with other African institutions, research excellence, and student success stories.  The UFS invites all members of its community to contribute thought-provoking pieces to this virtual celebration of Africa Month. Selected contributions will be presented on the university's website and social media.

Among other formats, contributions may take the format of

  • recorded performing art performances (e.g., solo music or poetry);
  • virtual visual art presentations;
  • written poetry;
  • songs;
  • short thought/opinion pieces, which can also be published in mainstream media; or
  • topical academic writings.

Please share a brief written proposal explaining your planned contribution by 30 April 2021. The proposal should not exceed 300 words and should be emailed to Cornelius Hagenmeier (hagenmeiercca@ufs.ac.za) or Prof Colin Chasi (ChasiCT@ufs.ac.za).

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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