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18 August 2021 | Story ANDRÉ DAMONS | Photo ANDRÉ DAMONS
Dr Osayande Evbuomwan, a Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, always wanted to specialise in an area of medicine that was novel, innovative, intriguing and involved a lot of opportunities for groundbreaking research

Dr Osayande Evbuomwan, Senior Lecturer and Medical Specialist in the Department of Nuclear Medicine, Faculty of Health Sciences, at the University of the Free State (UFS) always wanted to specialize in an area of medicine that was novel, innovative, intriguing and involved many opportunities for groundbreaking research.

This passionate medical man, who joined the UFS in 2019, is behind his department using Lutetium 177 PSMA (Lu-177 PSMA) therapy to treatment metastatic castrate resistant prostate cancer (MCRPC) – an advanced stage prostate cancer. 
The UFS and the Free State province can now join other South African universities, like the University of Pretoria, University of the Witwatersrand, and other provinces in using this method to treat MCRPC patients. 

Built for this job

Dr Evbuomwan explains nuclear medicine is a medical specialty that involves the use of unsealed sources of radiation in the form of radioisotopes for the diagnosis and treatment of various disease conditions including cancers.
“It’s novelty and opportunity for research and ability to diagnose and treat disease conditions in one specialty attracted me to this field. I always wanted to be a doctor. I see it as a calling. It was also something my mum discovered while I was growing up as a child. In my next life, I would choose to be a medical doctor again,” he says.

“I was built for this job and it is always my joy to have the opportunity to carry out my work. We have been well-trained for this; we support all our skills with prayers. We try to give our patients the very best,” says Dr Evbuomwan, who is originally from Benin City, Edo state, Nigeria. 

After graduating as a nuclear medicine specialist from Wits University, Dr Evbuomwan moved to the City of Roses after a work opportunity opened. He saw it as an opportunity to showcase his talents.

“I have been privileged to receive training in this treatment during my residency training at Wits. I treated a few of these patients during my training and the results were amazing. The University of Pretoria has also been involved with this treatment, with some amazing results that are recognised worldwide. 

“This was enough to convince me to push for our department to also join the powerhouses and offer this treatment to patients who need it. With the influence of a very understanding head of department, Dr Gerrit Engelbrecht, we have been successful in pushing for the commencement of this treatment at our facility,” says Dr Evbuomwan.

Important treatment
According to him, the availability and expertise of Lutetium 177 PSMA (Lu-177 PSMA) therapy to treat MCRPC is very important for the Free State and the UFS, as it is able to offer an option for patients who do not qualify for available conventional treatment and/or who have failed the first line of conventional treatment. 

“In the majority of patients this treatment offers improved quality of life, disease-free progression and improved overall survival. It also alleviates the constant bone pains these patients have to go through daily. To be able to offer this treatment puts the university and the province on the map alongside other top institutions in and outside the country. It also offers opportunity for research,” says Dr Evbuomwan.

He believes with a PET/CT camera for proper staging of these patients with cancer the UFS would be able to expand the treatment of patients suffering from this deadly illness. Currently the university does not possess such a camera and has to use lesser methods in identifying the right patients for this therapy.

News Archive

Breeding of unique game requires a balance between conservation and sustainable use
2014-05-20

 

Game bred for qualities such as unconventional hair colour or horn quality, may on the long term have unexpected consequences for biodiversity and game farming.

This is according to the inaugural lecture of Prof Paul Grobler from the Department of Genetics at the University of the Free State (UFS).

Prof Grobler feels that the consequences of selective breeding should be examined carefully, as there is currently much speculation on the subject without sound scientific information to back it.

“At the moment, colour variation invokes much interest among game farmers and breeders. Unusual colour variants are already available in different game species. These unusual animals usually fetch much higher prices at auctions compared to prices for the ‘normal’ individuals of the species.”

Examples of these unusual variants are springbuck being bred in white, black or copper colours, the black-backed or ‘saddleback’ impala, and the gold-coloured and royal wildebeest.

A black-backed impala was recently sold for R5,7 million.

“Based on genetic theory, good reason exists why these practices need to be monitored, but one should also take care not to make the assumption that selective breeding will inevitably lead to problems,” warns Prof Grobler.

Grobler says that negative characteristics in a species can sometimes unwittingly be expressed during the selection process for a unique colour. “It is seen, for example, in purebred dogs where the breeding of a new race sometimes brings underlying genetic deviations in the species to the front.” He also believes that some of these animals may not be able to adapt to changing environmental conditions.

“However, one should also look at the positive side: because of the good demand for game, including unusual variants, there is much more game in South Africa today than in many decades. Balance should be found between the aims of conservation and the sustainable utilisation of game.”

Research at the UFS’s Department of Genetics is now trying to establish the genetic effects of intensive game breeding and predict the impact on biodiversity.

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