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19 July 2021 | Story Lunga Luthuli | Photo Supplied
Fletcher Hiten, Chief Bioanalyst at FARMOVS, next to Aurora.
The Bioanalytical Services Division (BASD) at FARMOVS comprises a group of skilled and passionate scientists involved in the quantification of drugs, metabolites, and biomarkers in various biological matrices. One of their Analytical Science experts, Fletcher Hiten, explains what sets their team apart from the rest.

“Over the past 47 years, we have developed almost 600 validated assay methods. Most of these methods are for the analysis of ‘small’ molecules using chromatographic techniques such as LC-MS/MS, GC-MS, and HPLC, although LC-MS/MS is the technique of choice. New bioanalytical assays are continuously being development and validated in adherence to international regulatory guidelines set by the US-FDA and European Medicines Agency (EMA),” says Hiten.

“Recently, we decided to enhance our capabilities by recruiting exceptional talent. The newest member of the FARMOVS team is Aurora, a SCIEX Triple Quad™ 7500 LC-MS/MS mass analyser. Aurora is Latin for ‘dawn’: the beginning of a new era, especially one considered favourable. The SCIEX 7500 is currently marketed as the most sensitive triple quadrupole mass spectrometer available, allowing for sub-picogram/ml quantification. This means that Aurora will set FARMOVS apart from other clinical research organisations (CROs), creating an exciting and favourable landscape for clients to explore new partners in research.” 

Hiten stated: “If there was ever a time to move your next study to FARMOVS, it is now. To have Aurora on our team has many advantages, given that our clients can access unprecedented analytical sensitivity, which enables the quantification of pharmacokinetic (PK) profiles of drugs that have very low systemic absorption. These include predominantly local acting drugs, such as plasma concentrations of respiratory drugs (e.g., tiotropium and ipratropium), topically applied creams and ointments, and ophthalmology drops with ultra-sensitivity.”

“In addition, the quantification of drugs in low-volume matrices will also be exponentially enhanced, enabling the quantification of body fluids, where only a few microlitres can be collected, for example vaginal fluid, dried blood spots, cerebrospinal fluid, aqueous humour, synovial fluid, and epidermal micro-dialysis lysate – to name a few. The quantification of absorbed exogenous drugs into tissue, like vaginal biopsies and hair follicles, is also possible,” added Hiten. 

“And finally, multiple analyte analysis. In this case, the collected blood sample needs to be split into multiple aliquots for analysis, for example drug-drug interaction (DDI) studies with the Basel cocktail. The smaller sample volumes will allow more frequent sampling to be feasible and thus more accurate DDI interpretation,” Hiten explains.

“As a bio-analyst, one is seldom surprised. However, Aurora has already opened doors to new frontiers for our entire team and we cannot wait to do some more exploration,” says Hiten. 

To find out more about what Aurora and the FARMOVS team can do for your study, email business@farmovs.com. 

News Archive

UFS to accredit providers of Off-Campus Accommodation to students in Bloemfontein
2017-06-30

The University of the Free State (UFS) has embarked on a process to accredit off-campus accommodation service providers in Bloemfontein who provide accommodation to its students.

“The decision to accredit off-campus accommodation service providers comes from a concern from the university management about the safety of students and the conditions under which some of our students live in off-campus accommodation. Student accommodation is a significant aspect of the success of the UFS and consequently good quality accommodation is important for each individual student to be successful in his/her studies,” says Mr Quintin Koetaan, Senior Director: Housing and Residence Affairs at the UFS.

The accreditation process entails a list of primary requirements, drafted with the cognisance of the Mangaung Metropolitan Municipality, in terms of off-campus accommodation to which private providers must adhere in order to be accredited by the university. The requirements are in line with the Policy on the Minimum Norms and Standards for Student Housing at Public Universities (Government Gazette 39238, dated 29 September 2015).

According to Koetaan, the norms and standards as set out in the policy establish the foundation and assessment criteria for such accreditation of service providers by the UFS. “It has become necessary for the UFS to have a policy on off-campus accommodation, in order to protect the rights and interests of our students and that of the university,” says Koetaan.

Some of the primary requirements for accreditation by the UFS include the number of students that may be accommodated in each room, the quality of kitchens and kitchenettes, the number of ablution facilities, the existence of common rooms and house rules, general maintenance and cleaning, compliance with  relevant national, regional, and municipal legislative requirements regulating health and safety, provision for adequate access to the facility/establishment in case of medical and/or psychological emergency assistance being required by students, and the provision for access to emergency electricity and water facilities. Off-campus private accommodation service providers must also be in possession of approved Municipal building plans of their student accommodation facilities, as well as evidence confirming their compliance with these plans.

“Landlords and agents are also advised to become more involved in their student homes and to ensure that their properties are in good condition and secure enough for students to live in,” says Koetaan.

Off-campus private accommodation service providers have until 31 July 2017 to apply for accreditation. More information and application documentation for accreditation can be obtained by sending an email to housing@ufs.ac.za

Released by:
Lacea Loader (Director: Communication and Brand Management)
Telephone: +27 51 401 2584 | +27 83 645 2454
Email: news@ufs.ac.za | loaderl@ufs.ac.za
Fax: +27 51 444 6393

 

 

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