Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
19 July 2021 | Story Lunga Luthuli | Photo Supplied
Fletcher Hiten, Chief Bioanalyst at FARMOVS, next to Aurora.

The Bioanalytical Services Division (BASD) at FARMOVS comprises a group of skilled and passionate scientists involved in the quantification of drugs, metabolites, and biomarkers in various biological matrices. One of their Analytical Science experts, Fletcher Hiten, explains what sets their team apart from the rest.

“Over the past 47 years, we have developed almost 600 validated assay methods. Most of these methods are for the analysis of ‘small’ molecules using chromatographic techniques such as LC-MS/MS, GC-MS, and HPLC, although LC-MS/MS is the technique of choice. New bioanalytical assays are continuously being development and validated in adherence to international regulatory guidelines set by the US-FDA and European Medicines Agency (EMA),” says Hiten.

“Recently, we decided to enhance our capabilities by recruiting exceptional talent. The newest member of the FARMOVS team is Aurora, a SCIEX Triple Quad™ 7500 LC-MS/MS mass analyser. Aurora is Latin for ‘dawn’: the beginning of a new era, especially one considered favourable. The SCIEX 7500 is currently marketed as the most sensitive triple quadrupole mass spectrometer available, allowing for sub-picogram/ml quantification. This means that Aurora will set FARMOVS apart from other clinical research organisations (CROs), creating an exciting and favourable landscape for clients to explore new partners in research.” 

Hiten stated: “If there was ever a time to move your next study to FARMOVS, it is now. To have Aurora on our team has many advantages, given that our clients can access unprecedented analytical sensitivity, which enables the quantification of pharmacokinetic (PK) profiles of drugs that have very low systemic absorption. These include predominantly local acting drugs, such as plasma concentrations of respiratory drugs (e.g., tiotropium and ipratropium), topically applied creams and ointments, and ophthalmology drops with ultra-sensitivity.”

“In addition, the quantification of drugs in low-volume matrices will also be exponentially enhanced, enabling the quantification of body fluids, where only a few microlitres can be collected, for example vaginal fluid, dried blood spots, cerebrospinal fluid, aqueous humour, synovial fluid, and epidermal micro-dialysis lysate – to name a few. The quantification of absorbed exogenous drugs into tissue, like vaginal biopsies and hair follicles, is also possible,” added Hiten. 

“And finally, multiple analyte analysis. In this case, the collected blood sample needs to be split into multiple aliquots for analysis, for example drug-drug interaction (DDI) studies with the Basel cocktail. The smaller sample volumes will allow more frequent sampling to be feasible and thus more accurate DDI interpretation,” Hiten explains.

“As a bio-analyst, one is seldom surprised. However, Aurora has already opened doors to new frontiers for our entire team and we cannot wait to do some more exploration,” says Hiten. 

To find out more about what Aurora and the FARMOVS team can do for your study, email business@farmovs.com

News Archive

Food insecurity at university campuses under the spotlight
2015-08-20

 

"Food insecurity is   becoming an increasing problem at South African universities, much to the surprise of university managers." - Dr Louise van den Bergh, senior lecturer and researcher at our department of Nutrition and Dietetics

More than 70% of early university dropouts in the country were forced to abandon their tertiary studies because of food insecurity and financial need.

This was one of the conclusions drawn during the first higher education colloquium on food insecurity. The colloquium was hosted on by the University of the Free State (UFS) on the Bloemfontein Campus on 14 August 2015, where researchers from universities across the country shared their research about food insecurity on university campuses.

In South Africa, university campuses are not usually associated with food insecurity but, over the last few years, tertiary education has become more accessible to an increasing number of first-generation students and students from low-income households.

Some of the research indicated that students from lower-income households are often lacking financially, even with bursaries. The research has also shown that students frequently have to use part of their bursary money to support their families. This results in students not having enough money to buy food, which means they will do almost anything to get food.

A study by the UFS Department of Nutrition and Dietetics found that as many as 60% of our students are food insecure, and experience hunger frequently. This study was the first of its kind in South Africa. In 2011, the UFS launched the No Student Hungry Bursary Programme to provide food bursaries to food-insecure students.

At the opening of the colloquium, Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, said by helping students with a basic commodity like food, you give them much more than food; you give them humanity and dignity.

Dr Louise van den Bergh, senior lecturer and researcher in the UFS Department of Nutrition and Dietetics, explains that the problem is considerably more complex than just providing for students financially.

Dr Van den Bergh says that funders need to reassess bursaries, keeping issues such as food insecurity in mind, and not focusing just on tuition.

Research presented at the colloquium: (PDF's van die slides)

UFS Food environment and nutritional practices

UFS Skeleton in the University closet

UKZN Achieving food security

UKZN Food security and academic performance

UKZN Hunger for knowledge

UKZN Perceptions of food insecurity complexities

UW Food acquisition struggles

 

 

 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept