Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
19 July 2021 | Story Lunga Luthuli | Photo Supplied
Fletcher Hiten, Chief Bioanalyst at FARMOVS, next to Aurora.

The Bioanalytical Services Division (BASD) at FARMOVS comprises a group of skilled and passionate scientists involved in the quantification of drugs, metabolites, and biomarkers in various biological matrices. One of their Analytical Science experts, Fletcher Hiten, explains what sets their team apart from the rest.

“Over the past 47 years, we have developed almost 600 validated assay methods. Most of these methods are for the analysis of ‘small’ molecules using chromatographic techniques such as LC-MS/MS, GC-MS, and HPLC, although LC-MS/MS is the technique of choice. New bioanalytical assays are continuously being development and validated in adherence to international regulatory guidelines set by the US-FDA and European Medicines Agency (EMA),” says Hiten.

“Recently, we decided to enhance our capabilities by recruiting exceptional talent. The newest member of the FARMOVS team is Aurora, a SCIEX Triple Quad™ 7500 LC-MS/MS mass analyser. Aurora is Latin for ‘dawn’: the beginning of a new era, especially one considered favourable. The SCIEX 7500 is currently marketed as the most sensitive triple quadrupole mass spectrometer available, allowing for sub-picogram/ml quantification. This means that Aurora will set FARMOVS apart from other clinical research organisations (CROs), creating an exciting and favourable landscape for clients to explore new partners in research.” 

Hiten stated: “If there was ever a time to move your next study to FARMOVS, it is now. To have Aurora on our team has many advantages, given that our clients can access unprecedented analytical sensitivity, which enables the quantification of pharmacokinetic (PK) profiles of drugs that have very low systemic absorption. These include predominantly local acting drugs, such as plasma concentrations of respiratory drugs (e.g., tiotropium and ipratropium), topically applied creams and ointments, and ophthalmology drops with ultra-sensitivity.”

“In addition, the quantification of drugs in low-volume matrices will also be exponentially enhanced, enabling the quantification of body fluids, where only a few microlitres can be collected, for example vaginal fluid, dried blood spots, cerebrospinal fluid, aqueous humour, synovial fluid, and epidermal micro-dialysis lysate – to name a few. The quantification of absorbed exogenous drugs into tissue, like vaginal biopsies and hair follicles, is also possible,” added Hiten. 

“And finally, multiple analyte analysis. In this case, the collected blood sample needs to be split into multiple aliquots for analysis, for example drug-drug interaction (DDI) studies with the Basel cocktail. The smaller sample volumes will allow more frequent sampling to be feasible and thus more accurate DDI interpretation,” Hiten explains.

“As a bio-analyst, one is seldom surprised. However, Aurora has already opened doors to new frontiers for our entire team and we cannot wait to do some more exploration,” says Hiten. 

To find out more about what Aurora and the FARMOVS team can do for your study, email business@farmovs.com

News Archive

International Literacy Day an opportunity to reach out
2016-09-08

Description: International Literacy Day 2016 Tags: International Literacy Day 2016

Sasol Library
Photo: Sonja Small


Library and Information Services and Community Engagement office promote literacy.

Fifty years ago UNESCO officially proclaimed 8 September International Literacy Day to actively mobilise communities and to promote literacy as an instrument of empowering individuals and society. This year this great milestone will be celebrated under the banner “reading the past, writing the future”. As we commemorate 50 years we should ask ourselves whether Illiteracy has been eradicated or not.

As part of its outreach programme, Library and Information Services, in collaboration with the office of Community Engagement, for the first time jointly celebrate International Literacy Day and invited members of the community to a book launch which took place at Lefikeng High School in Botshabelo on 8 September 2016. The programme also included the establishment of a small library at the school, and on 15 September, a writer’s day event will be held together with the Department of African Languages on the Bloemfontein Campus.

The book, “Amazing Grace”, was written by Free State-born writer, Charles Dunn. Dunn took the opportunity to speak to students and the community of Botshabelo about his inspiration for writing the book, as well as take them through his journey of life, from surviving drug addiction to imprisonment, and how he finally changed his life to become an author.

In working towards eradicating illiteracy, the Library and Information Services has hosted a number of book launches in the past, to encourage a culture of reading and writing among academia, students and surrounding communities, as well as opportunities for them to network with local and international authors. Feedback from these events bears testimony that indeed the library is successful in creating spaces for lifelong learning.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept