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27 September 2022 | Story André Damons | Photo Charl Devenish
Prof Martin Nyanga
Prof Martin Nyaga, Associate Professor in the UFS-NGS Unit and Director of the WHO Collaborating Centre (WHO CC), says the UFS researchers – through the Division of Virology/NHLS and the UFS-NGS Unit – were involved in the major publication as part of the NGS-SA consortium from the study design phase, ethics applications, and throughout the study.

Researchers from the University of the Free State (UFS) Next Generation Sequencing (UFS-NGS) Unit and Division of Virology/ National Health Laboratory Service (NHLS) were part of a major publication featuring hundreds of authors from Africa who did research on the evolution of SARS-CoV-2.

The scientific publication in the journal Science (impact factor 47.728) featured more than 300 scientists and public health officials from Africa and abroad, who worked together to look into the evolution of SARS-CoV-2, the viral agent causing COVID-19. It was the first collaborative study of this nature conducted in Africa during the COVID-19 global pandemic. The publication became available online on 15 September this year. 

According to a press release by the Centre for Epidemic Response and Innovation (CERI) at Stellenbosch University and the KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at the University of KwaZulu-Natal (UKZN), this was the largest consortium of African scientists and public health institutions working together to support data-driven COVID-19 response in Africa. This collaboration was led by two labs (CERI and KRISP) and the Network for Genomic Surveillance in South Africa (NGS-SA) consortium, of which the UFS-NGS Unit and Division of Virology are founding members, in close coordination with the Africa CDC, WHO/AFRO and 300 other institutions across the continent.

It is an awesome feeling

Prof Martin Nyaga, Associate Professor in the UFS-NGS Unit and Director of the WHO Collaborating Centre (WHO CC), says the UFS researchers – through the Division of Virology/NHLS (coordinated by Prof Dominique Goedhals and Mr Philip Armand Bester) and also the UFS-NGS Unit (Prof Nyaga, Dr Peter Mwangi, Mr Milton Mogotsi, and Mr Emmanuel Ogunbayo) – were involved as part of the NGS-SA consortium from the study design phase, ethics applications, and throughout the study, processing the SARS-CoV-2 positive samples for whole-genome sequencing, thus generating significant sequence data of the SARS-CoV-2 variants circulating in South Africa.

“It is an awesome feeling to be part of the solution in resolving the COVID-19 pandemic by providing data that would track variants in real time and data used to implement prophylactic solutions, such as vaccine development, against a virus that was a global threat,” says Prof Nyaga. 

According to him, the utility of next-generation sequencing technologies in understanding genomics of diseases was clearly demonstrated in this study and will assist in addressing future diseases/pandemics. These genomic studies provide deeper insights regarding diseases, and they will provide timely solutions to solving diseases affecting the Mother Continent.

UFS Free State variants study

Prof Nyaga says their Free State variants study, which was also recently published in the journal Frontiers in Virology, performed analysis of samples from patients who tested positive for SARS-CoV-2 throughout all the COVID-19 waves. “We aimed to determine whether the variants driving the epidemic waves at the national level were also driving the epidemic waves at the local level, in the context of the Free State province. The data further indicates that SARS-CoV-2 variants driving the epidemic waves in the Free State at the local level correlated with the ones driving the epidemic waves at the national level. Findings from this study highlight the importance of continued genomic surveillance and monitoring of the circulating SARS-CoV-2 variants to inform public health efforts and ensure adequate control of the ongoing pandemic. 

“Our data has been incorporated into the analyses of the bigger continent-wide collaboration on genomics surveillance to determine how the majority of COVID-19 variants were introduced into Africa, which has now been published in the journal Science,” says Prof Nyaga.  
The publication highlights that sustained investment in diagnostics and genomic surveillance in Africa was needed to not only help combat SARS-CoV-2 on the continent, but to establish a platform to address the emerging, re-emerging, endemic infectious disease threats, such as Ebola, HIV/Aids, TB, malaria, and enteric disease-causing viruses.

News Archive

Emma Sadleir talks about social media etiquette
2016-05-18

Description: Emma Sadlier Tags: Emma Sadlier

Emma Sadleir
Photo: Supplied

“We have all become celebrities, we have become social figures because of our power to publish information. We have all become brands, and we need to protect our brand. Digital content is sometimes dangerous content,” said Sadleir.

On 11 May 2016, the University of the Free State, in collaboration with the Postgraduate School, hosted, Emma Sadleir, a leading social media expert, in the Equitas Auditorium on the Bloemfontein Campus. She is an admitted advocate, specialising in social media law.  Dr Henriette van den Berg, Director of the Postgraduate School, described Sadleir’s presentation as a privilege for all the staff and students who attended.

Sadleir said that there are two important rules that staff and students of an institution should try to follow. The first is not to bring the name of the institution into disrepute; and the second is not to breach the goodwill of the institution or, in other words, not to bite the hand that feeds you.

“The common law, even if there is no policy, is that anything that brings the company into disrepute can lead to disciplinary consequences up to termination,” said Sadleir.

Sadleir focused on hate speech and free speech, stating that free speech is a right that is entrenched in the constitution, but, like every other right, it has limitations. She mentioned Penny Sparrow, Matt Theunissen, Velaphi Khumalo, and Judge Mabel Jansen, all of whom have been lambasted by the public over their racist posts on social media. Sadleir stressed that, even on social media, content has to be within the confines of the law, and people must remember our rights are not absolute. We have a lot of freedoms, but no one cannot disseminate hate speech.

“Would you publish whatever you thinking on a billboard, close to a busy highway with your name, picture and employers details or the institution you studying at? If you have no grounds to justify the comment, do not post it,” warned Sadlier.  

According to the South African Bill of Rights, everyone has the right to privacy, but an expectation of privacy has to be enforced. She said people over-document their lives on social media, decreasing your right to privacy drastically. “It is like CCTV footage of your life. It is simple, the more you take care of your privacy, the more you have,” said Sadleir.

Sadleir said it was important for Facebook users to have privacy settings where they can review posts where they are tagged. According to Sadleir, managing your reputation is not only limited to what you post about yourself but also managing what others post about you.

She cited a 2013 case in the Pretoria High Court in which a new wife wrote a scandalous Facebook post about her husband’s ex-wife, tagging the husband in the post. The courts found both the new wife and the husband guilty of defamation.

“If you have been tagged in something but have not been online and seen the content, you are then an innocent disseminator. The moment you are aware of the post you are liable for the content,” said Sadleir.

“It takes 20 years to build a reputation and five minutes to ruin it. If you think about that, you'll do things differently,” Sadleir said, concluding her presentation with the quotation from Warren Buffet.

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