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14 May 2019 | Story Thabo Kessah | Photo Tsepo Moeketsi
Prof Ashafa
Prof Ashafa’s research documents plants used by the Basotho in the management of different ailments.
The Phytomedicine and Phytopharmacology Research Programme (PPRP) in the Department of Plant Sciences on the Qwaqwa Campus researches the biological effects of medicinal plants used in the folkloric medicine of the Eastern Free State, particularly to explore the values and contribution of indigenous knowledge systems (IKS) towards broader scientific research. This is according to the programme’s principal investigator and researcher, NRF C2-rated researcher, Professor Anofi Ashafa. 

 “Our research is mainly aimed at documenting plants used by the Basotho in the management of different ailments and to further discover, isolate, and purify active phytoconstituents that are responsible for disease curation or amelioration, thereby assisting in the global promotion of accessible and affordable medication in developing countries,” said Prof Ashafa. 

Since 2012, the PPRP has worked extensively on Basotho medicinal plants (BMP) used as antimicrobials, antioxidants, antidiabetics, antitubercular, anticancer, anthelmintic, and antidiarrheal agents, starting from biological activities up to the  evaluation of the toxicity of these plants for the kidney, liver, and heart functions in order to establish safe dosage parameters. These activities have led to the discovery of four potent antidiabetic biomolecules that are awaiting the processes of patency and commercialisation. Additional outputs include 104 published peer-reviewed articles , 7 postdoctoral fellows, 6 PhDs, 9 master’s, and 16 honours graduates. 

“Our research informs teaching and the development of expertise in ethnobotany, 
phytomedicine, and phytopharmacology in order to contribute to the National Development Plan (NDP) through human capacity development, skills, and knowledge transfer.

The group is also investigating some medicinal plants on the endangered red list of the South African National Biodiversity Institute (SANBI), through micropropagation and field trials as well as proposing conservation strategies to preserve these valuable species.

The PPRP consists of postdoctoral fellows, PhD, master’s, and honours students and research is done in collaboration with several local and international universities as well as the Agricultural Research Council of South Africa. 


News Archive

Darwin lecture focuses on the genetic foundation of evolution
2009-05-22

 
The Department of Genetics at the University of the Free State (UFS) recently made their contribution to the story of life and survival by presenting two lectures on The genetic foundation of evolution. Prof. Johan Spies, Head of the Department of Genetics at the UFS discussed the variation that was created by mutations and how this variation was enhanced by re-combination. He also pointed out that these methods contributed relatively little to the gene pool of a species and that the expansion of the gene pool primarily took place by means of chromosome evolution. The latter also contributed to the creation of isolation mechanisms to prevent hybridism. He further emphasised the multitude of deviations of mendelian heredity, which contributed to more variation within a species.

Prof. Paul Grobler, Associate Professor from this department, next pointed out how natural selection played a role to form new species. He used various examples to indicate how the process took its course, for example, lactose intolerance. He also reported out that the man on the street mostly believed that Darwin with his theory of the survival of the fittest meant that the physically strongest species would survive. It was more a case of the one that could reproduce the fastest and the most, that would survive, he stated.

Present at the occasion were, from left front: Ms Letecia Jonker, student, Prof. Grobler, Ms Paula Spies, lecturer at the Department of Genetics and Ms Zurika Odendaal, junior lecturer at the Department of Genetics; back: Prof. Spies.
Photo: Stephen Collett

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