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11 April 2018 Photo Leonie Bolleurs
First accredited ICS training in SA presented at UFS
Prof Andries Jordaan, Head of DiMTEC, with Greg Archer from the United States Forest Services, and Yong Sebastian Nyam, a DiMTEC PhD student from Cameroon.

The University of the Free State’s (UFS) Disaster Management Training and Education Centre for Africa (DiMTEC) and the Free State Umbrella Fire Protection Association (FSUFPA) presented the first training exercise in the Free State, offering practical experience regarding the implementation of the Incident Command System (ICS) under simulated emergency conditions.

An Exercise Coordination Team (ECT), consisting of US instructors, under the leadership of Mike Kopitzke from the United States Forest Services, together with Johann Breytenbach from FSUFPA and supported by local personnel, facilitated the exercise.

Training complete with sand table exercise 

This dual site desktop exercise took place at the Rooipoort Training Centre outside Dewetsdorp and the DiMTEC offices in the Agriculture Building on the UFS Bloemfontein Campus. The Incident Management Team (IMT) training – complete with a sand table exercise   was presented at Rooipoort, At the same time a simulation of an Emergency Operations Centre (EOC) was offered at the DiMTEC offices. 

According to Prof Andries Jordaan, Head of DiMTEC, the exercise was based on a variety of actual scenarios that had previously taken place elsewhere in the Free State. The exercise simulated a train and bus accident on the Thaba Nchu road. “Using an incident like this keeps the training realistic and relevant,” he said.

In these exercises the work of different departments, including South African Police Services (SAPS), South African National Defence Force (SANDF), Transnet, Spoornet, Traffic Department, and Eskom are coordinated. “We would like to work with the National Disaster Management Centre (NDMC) to implement a uniform Incident management system in South Africa where all departments speak the same language and have the same understanding of the role and responsibilities of a command structure,” Prof Jordaan said.

Accredited training the outcome
In 2017 Prof Jordaan, General Elias Mahlabane from the SAPS, and Johan Breytenbach from the FSUFPA, attended an incident command course in California in the US. They were introduced to the National Incident Management System (NIMS) in the US. The system was implemented after lessons learned during 9/11. “According to the NIMS structure, all government organisations at all levels, as well as emergency agencies, had to standardise terminology and systems,” said Prof Jordaan.

Insight gained during the visit and a work relationship with the United State Forest Services, provided Prof Jordaan and Breytenbach the necessary background to conduct training for incident management teams.

Currently DiMTEC is offering accredited ICS 100, 200 and 300 courses. To qualify as incident command managers, students need to attend the ICS courses together with the practical training. As part of the training they also need to shadow a qualified ICS manager during two real incidents. These courses are taking place in conjunction with the FSUFPA. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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