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24 August 2018 Photo Igno van Niekerk
Chemistry changing the world to create a better future
These practical applications of Chemistry are part of the relevant and practically applicable research Prof André Roodt (far left) and his research group are involved in. With him are Dr Ebrahiem Botha, Post-doctoral fellow; Pheelo Nkoe, PhD student; Shaun Redgard, MSc student; and Dr Orbett Alexander, Post-doctoral fellow

Some people have a gift for explaining the most complex concepts in a way anyone could understand. Combine this gift with passion, energy, and enthusiasm, and you are close to describing a meeting with Prof André Roodt

Prof Roodt not only teaches Chemistry, he lives it. He has published more than 320 papers, lectured internationally more than 100 times, and has guided 35 PhD and 48 MSc students to complete their degrees. These figures are likely to conjure up visions of a dusty academic working on pie-in-the-sky theories. 

Adding value

Within minutes you are made aware of the fact that Chemistry is not only a subject confined to classrooms and labs. It is a means of changing the world through research to create a better future. In academic terms, Prof Roodt and his team are involved in ‘Homegeneous Catalysis’, ‘Radiopharmacy: Theranostics’, ‘Metal Benefication’, and ‘Conversion of carbon dioxide and water’. And just when you start to remember how terrifying high-school Chemistry was, Prof Roodt explains the practical nature of what they are doing.

Few of us are aware of the exact processes that produce fuel for our cars, although we probably know that these processes have side effects which are usually detrimental to the environment; but what if the by-products of these processes can be turned into speciality chemicals which could add value in different ways?

Ever wondered how medication know where to go in your body? Well – just imagine highly specialised (clever) pharmaceutical agents giving off their own ‘light’, knowing exactly where to go, showing you where they are going, and knowing what to do in order to provide information and interact with specific cells in your body to assist in healing cells and fighting disease. Exciting.

Passionate people

But, as they say in the ads, that is not all; imagine better ways to generate power, using the natural processes in plants to increase natural oxygen where needed, and to be able to change oxygen levels in the environment.

These practical applications of Chemistry are part of the relevant and practically applicable research Prof Roodt and his research group are involved in.

When you leave Prof Roodt’s office, you realise that this is what the UFS is all about: Global impact. World-class research. Passionate people. And seizing the opportunity to create the future.

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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