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24 August 2018 Photo Igno van Niekerk
Chemistry changing the world to create a better future
These practical applications of Chemistry are part of the relevant and practically applicable research Prof André Roodt (far left) and his research group are involved in. With him are Dr Ebrahiem Botha, Post-doctoral fellow; Pheelo Nkoe, PhD student; Shaun Redgard, MSc student; and Dr Orbett Alexander, Post-doctoral fellow

Some people have a gift for explaining the most complex concepts in a way anyone could understand. Combine this gift with passion, energy, and enthusiasm, and you are close to describing a meeting with Prof André Roodt

Prof Roodt not only teaches Chemistry, he lives it. He has published more than 320 papers, lectured internationally more than 100 times, and has guided 35 PhD and 48 MSc students to complete their degrees. These figures are likely to conjure up visions of a dusty academic working on pie-in-the-sky theories. 

Adding value

Within minutes you are made aware of the fact that Chemistry is not only a subject confined to classrooms and labs. It is a means of changing the world through research to create a better future. In academic terms, Prof Roodt and his team are involved in ‘Homegeneous Catalysis’, ‘Radiopharmacy: Theranostics’, ‘Metal Benefication’, and ‘Conversion of carbon dioxide and water’. And just when you start to remember how terrifying high-school Chemistry was, Prof Roodt explains the practical nature of what they are doing.

Few of us are aware of the exact processes that produce fuel for our cars, although we probably know that these processes have side effects which are usually detrimental to the environment; but what if the by-products of these processes can be turned into speciality chemicals which could add value in different ways?

Ever wondered how medication know where to go in your body? Well – just imagine highly specialised (clever) pharmaceutical agents giving off their own ‘light’, knowing exactly where to go, showing you where they are going, and knowing what to do in order to provide information and interact with specific cells in your body to assist in healing cells and fighting disease. Exciting.

Passionate people

But, as they say in the ads, that is not all; imagine better ways to generate power, using the natural processes in plants to increase natural oxygen where needed, and to be able to change oxygen levels in the environment.

These practical applications of Chemistry are part of the relevant and practically applicable research Prof Roodt and his research group are involved in.

When you leave Prof Roodt’s office, you realise that this is what the UFS is all about: Global impact. World-class research. Passionate people. And seizing the opportunity to create the future.

News Archive

Chemistry postgraduates tackle crystallography with eminent international researcher
2017-04-04

Description: Dr Alice Brink  Tags: Dr Alice Brink

Department of Chemistry senior lecturer, Dr Alice Brink(left),
hosted outstanding researcher, Prof Elspeth Garman (right)
from the University of Oxford in England to present a
crystallography lecture.
Photo: Rulanzen Martin



“Crystallography forms part of everyday life.” This is according to Prof Elspeth Garman, eminent researcher from the Department of Biochemistry, University of Oxford in England, who was hosted by Dr Alice Brink, Department of Chemistry at the University of the Free State (UFS) Bloemfontein Campus. Prof Garman presented a lecture in the Department of Chemistry, titled ‘104 years of crystallography: What has it taught us and where will it lead’. She also taught the postgraduate students how to refine and mount protein structures in cold cryo conditions at about -173°C.

What is Crystallography?
Crystallography is the scientific technique which allows for the position of atoms to be determined in any matter which is crystalline.
 
“You cannot complete Protein Crystallography without the five key steps, namely obtaining a pure protein, growing the crystal, collecting the data, and finally determining the structure and atomic coordinates,” said Prof Garman. Apart from teaching, she was also here to mentor and have discussions with UFS Prestige Scholars on how to face academic challenges in the professional environment.

Discovery of the first crystal structure of a TB protein

Prof Garman successfully determined the first crystal structure of a Tuberculosis protein (TBNAT), a project that took about 15 years of research. In partnership with the Department of Pharmacology at Oxford University and an outstanding PhD student, Areej Abuhammad, they managed to grow only one TBNAT crystal, one-fiftieth of a millimetre. They also managed to solve the structure and publish it.

Dr Alice Brink, Senior Lecturer in the Department of Chemistry, says, “It’s an incredible privilege to have Prof Garman here and to have her share her wisdom and knowledge so freely with the young academics.”

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