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30 August 2018 Photo Xolisa Mnukwa
Haemophilia workshop the first of its kind at UFS
The UFS Department of Haematology and Cell Biology is producing quality medical graduates, addressing the high demand for trained graduates. Dr Anneke van Marle, Haematologist in the department, presented a lecture to final-year medical students on muscle and soft-tissue bleeding in haemophilia.

The Medical and Scientific Advisory Council (MASAC) of the South African Haemophilia Foundation (SAHF) has identified a need for more in-depth training of junior doctors on the basic aspects of the bleeding disorder haemophilia. 

Addressing this need in the sector, the Department of Haematology and Cell Biology at the University of the Free State (UFS) recently hosted a training workshop specifically targeting final-year medical students before they enter practice.

The Novo Nordisk Haemophilia Foundation is sponsoring this countrywide haemophilia training.

According to Jaco Joubert, Senior Lecturer and Pathologist in the Department of Haematology and Cell Biology, the department is very active in the field of haemophilia treatment, research and training, with representation on the Executive Committee of the Medical and Scientific Advisory Council of the South African Haemophilia Foundation.

Function with confidence

“The UFS Department of Haematology and Cell Biology has taken a proactive approach, by being the first department in South Africa to offer this training course to final-year medical students at the UFS; an investment in the future. The department runs the Bloemfontein Haemophilia Treatment Centre – which is the main haemophilia treatment and referral centre for patients from the Free State and Northern Cape. It is therefore ideally positioned to offer such training to students,” said Joubert.

Proactive role

The training workshop empowered and equipped students with more extensive knowledge on the practical aspects of managing patients with haemophilia; the various treatment products currently available in South Africa and laboratory diagnostic approaches in complicated cases. “This will enable students to function with more confidence during their internship and community service years,” said Joubert. 

He believes a training workshop of this calibre showcases the proactive role the department and the university is taking in the advancement of haemophilia training in South Africa.

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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