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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Boyden Observatory turns 120
2009-05-13

 

At the celebration of the 120th year of existence of the UFS's Boyden Observatory are, from the left: Prof. Herman van Schalkwyk, Dean: Faculty of Natural and Agricultural Sciences at the UFS, Prof. Driekie Hay, Vice-Rector: Academic Planning at the UFS, Mr Ian Heyns from AngloGold Ashanti and his wife, Cheryl, and Prof. François Retief, former rector of the UFS and patron of the Friends of Boyden.
Photo: Hannes Pieterse

The Boyden Observatory, one of the oldest observatories in the Southern Hemisphere and a prominent beacon in Bloemfontein, recently celebrated its 120th year of existence.

This milestone was celebrated by staff, students, other dignitaries of the University of the Free State (UFS) and special guests at the observatory last week.

“The observatory provides the Free State with a unique scientific, educational and tourist facility. No other city in South Africa, and few in the world, has a public observatory with telescopes the size and quality of those at Boyden,” said Prof. Herman van Schalkwyk, Dean of the Faculty of Natural and Agricultural Sciences at the UFS.

The observatory, boasting the third-largest optical telescope in South Africa, has a long and illustrious history. It was established on a temporary site on Mount Harvard near the small town of Chosica, Peru in 1889. Later it was moved to Arequipa in Peru where important astronomical observations were made from 1891 to 1926. “However, due to unstable weather patterns and observing conditions, it was decided to move the Boyden Station to another site somewhere else in the Southern Hemisphere, maybe South Africa,” said Prof. Van Schalkwyk.

South Africa's excellent climatic conditions were fairly well known and in 1927 the instruments were shipped and the Boyden Station was set up next to Maselspoort near Bloemfontein. Observations began in September 1927 and in 1933 the new site was officially completed, including the 60 inch (1.5 m) telescope, which was then the largest optical telescope in the Southern Hemisphere. This telescope was recently refurbished to a modern research instrument.

The observatory has various other telescopes and one of them, the 13" refractor telescope, which was sent to Arequipa in 1891 and later to Bloemfontein, is still in an excellent condition. Another important telescope is the Watcher Robotic Telescope of the University College Dublin, which conducts many successful observations of gamma ray bursts.

“In the first few decades of the twentieth century, the Boyden Observatory contributed considerably to our understanding of the secrets of the universe at large. The period luminosity relationship of the Cepheid variable stars was, for example, discovered from observations obtained at Boyden. This relationship is one of the cornerstones of modern astrophysics. It is currently used to make estimates of the size and age of the universe from observations of the Hubble Space Telescope,” said Prof. Van Schalkwyk.

“The Boyden Observatory contributed to the university’s astrophysics research group being able to produce the first M.Sc. degrees associated with the National Space Science Programme (NASSAP) in the country and the Boyden Science Centre plays an important role in science and technology awareness of learners, teachers and the general public,” said Prof. Van Schalkwyk.

The Boyden Science Centre has also formed strong relationships with various institutions, including the South African Agency for the Advancement of Science and Technology (SAASTA) and the Department of Science and Technology. The centre has already conducted many different projects for the Department of Science and Technology, including National Science Week projects, as well as National Astronomy Month projects. It also serves as one of the hosts of SAASTA’s annual Astronomy Quiz.

Media Release:
Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
13 May 2009
 

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