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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

An incident-free recess for the UFS
2010-07-19

The improved security measures at the University of the Free State (UFS) have resulted in an incident-free recess on the Main Campus in Bloemfontein during the 2010 FIFA World Cup and the annual Volksblad Arts Festival.

The UFS provided accommodation for international spectators visiting the country for the World Cup and recently also hosted the hugely popular Volksblad Arts Festival without any security glitches.

These successes could be attributed to the hard work of staff members from various divisions at the UFS to ensure that the security was improved.

“The main question we had to deal with was: should our Main Campus be fenced off? This matter had been under discussion for quite some time. In order to ensure the feasibility thereof, a second impact study was done by a consulting engineer,” said Prof. Niel Viljoen, Vice-Rector: Operations at the UFS.

“This study has shown that, given the nature of activities on the campus and the access configuration, it would be difficult, if not impossible, to effectively control access to the campus, especially as far as visitors were concerned. Any type of access control measure would result in delays at the gates, which could have a major impact on the traffic flow, delays, costs and emissions.”

“It is important that our staff and students feel safe on the Main Campus, whether they are walking on campus or working in their offices. In that way we can ensure an environment that is conducive to staff and students to work and study,” he said.

Various measures are being implemented to make the campuses safer. These include, among others:

  • The installation of alarms in buildings on the Main Campus. The project for the South Campus has been completed and the installation of a new alarm system on the Qwaqwa Campus will start soon.

     
  • Staff and students will be required to wear identification cards once the new identification system has been put in place. These cards will allow access to all buildings.

     
  • Fences around the Main Campus are being repaired and the areas around these fences are being cleaned. This project should be completed by August 2010.

     
  • Lights will be installed in badly lit areas on the Main Campus. The first phase of this project includes the area between the Mooimeisiesfontein, Welwitschia and Vergeet-my-nie residences. This project will also be completed by August 2010.

     
  • The walkways on the Main Campus will be patrolled more frequently and effectively.

     
  • Contracted security workers will be utilised more effectively.

     
  • The monitoring of security cameras on the Main Campus on a 24/7 basis. “For this purpose the security room of our Protection Services is in the process of being upgraded,” said Prof. Viljoen.

The possibility of placing security cameras and panic buttons in parking areas and walkways is investigated.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
16 July 2010

 

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