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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Learning to serve, serving to learn
2013-10-18

 

At the Community Engagement Open Day were, at the back, from the left: Dr Choice Makhetha, Vice-Rector: External Relations; and Rev Billyboy Ramahlele, Director of Community Engagement. In front are, from the left: Selby Lengoabala, Betlehem Unit Manager; Councillor Job Tshabalala, Acting Executive Mayor; and Councillor Isaac Tshabalala, Strategic Manager in the office of the Executive Mayor of the Dihlabeng Local Municipality.
18 October 2013

The university held its first Community Engagement Open Day in order to honour outstanding individuals and highlight programmes that advance its civil responsibility. Hosted by the UFS Community Engagement Directorate, local community members, students and staff gathered in the Callie Human Centre at the Bloemfontein Campus, displaying what they do to empower communities.

Partners in Community Engagement (CE) and Service Learning (SL), local government, community-based research, student volunteer groups, Non-Profit Organisations (NPOs) and private business interacted with guests at their various information stalls. Faculties and departments displayed their distinctive programmes and demonstrated a renewed commitment to change lives through sharing knowledge, rendering services and fostering empowerment among communities.

In recognition of outstanding service, commitment and excellence in the field of community engagement and service learning, some staff members, researchers and some partners received the Vice-Rector’s Award for Community Engagement. Among them was Prof Matie Hoffman, who was honoured for his longstanding involvement in research at the Boyden Observatory. He is currently at the forefront of renovations for the planetarium at Naval Hill. In the category for external partners, REACH and Heidedal Childcare were awarded for demonstrating commitment towards their partnership with the university. The acting Executive Mayor, Job Tshabalala, also received an award on behalf of Dihlabeng Local Municipality Mayor, Tjhetane Mofokeng, for their involvement in education and social cohesion programmes. During his keynote address, the Director of Community Engagement, Rev Billyboy Ramahlele, emphasised the contribution that community engagement has on the two major strategic programmes of the university, namely the Academic and Human Projects. He pointed out that CE creates a platform on which students learn to appreciate human diversity in a real and unprotected set-up.

The interactions of the Open Day are expected to raise awareness, cultivate understanding among partners, encourage solid alliances and bring to the fore an acknowledgement of community engagement as the integral part of higher education.

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