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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Radboud University extends Institutional Agreement with UFS
2017-11-28

Description: 2017 International  Tags: internationalisation, Radboud University, Netherlands, institutional, Economic and Management Sciences, EU Erasmus+ programme, Business School  

Photo: Pixabay

The Office for International Affairs, in collaboration with the Business School, recently hosted delegates from Radboud University in the Netherlands to expand the existing partnership between the University of the Free State (UFS) and Radboud University.

Prof Joris Knoben and Charissa van Mourik visited the UFS to renew the Collaboration Agreement into an Institutional Agreement. The collaboration between the two universities was initially formalised as a Collaboration Agreement in August 2014. 

Zenzele Mdletshe, Senior Officer: North-South Cooperation: Internationalisation, says, “This partnership has been successful in implementing student exchange mobility, with about four students from Radboud University participating in student exchange programmes at the UFS for a period of six months.” The Dean of the Faculty of Economic and Management Sciences, Prof Hendri Kroukamp, has also been part of an International Week Programme at the Radboud University for the past three years.

Exploring student exchange mobility through funding
The negotiations focused on extending the collaboration, as well as exploring opportunities to have exchange mobility from the UFS to Radboud University. “The agreement is to look into opening cooperation through funding models such as the EU Erasmus+ programme in order to overcome the financial challenges which hinder mobility of UFS students,” Mdletshe says.

Postgraduate programmes considered for future development
Radboud University is said to consider the waiving of all costs related to the participation of three UFS students in a two-week summer school programme at their campus. In addition to this discussion, the development of the postgraduate exchange programme, research collaborations, and future exploration of joint master’s degree programmes are also a possibility. 
“The participants agreed that the universities would explore external funding opportunities, specifically with a view to developing reciprocal PhD mobility,” Mdletshe says.

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