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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Community engagement must be a core function of universities
2009-05-21

 
 Members of the NatCEMF Steering Committee are, from the left: Mr Jerome Slamat, Senior Director: Community Interaction, Stellenbosch University, Ms Beatrix Bouwman, Manager: Community Engagement, North-West University, Rev Kiepie Jaftha, Chief Director: Community Service, UFS and chairperson of the committee, Prof. Allan Femi Lana, Director: Institute for Rural Development and Community Engagement, Mangosuthu University of Technology, Prof. Seth Pollack, Fulbright Scholar, University of Western Cape (guest speaker at the meeting), Prof. Denver Hendricks, Director: Community Engagement, University of Pretoria, and Prof. Priscilla Daniels, Chairperson: Human Ecology and Research and CHESP Research Coordinator, University of the Western Cape.
Photo: Lacea Loader
 It is important that all tertiary institutions in South Africa should work together and commit themselves to advance the cause of community engagement in the country.

This was one of the main outcomes of the second meeting held by the National Community Engagement Manager’s Forum (NatCEMF) at the South Campus of the University of the Free State (UFS) in Bloemfontein recently. The meeting was attended by 34 representatives of 16 higher education institutions in the country.

“I am astounded at the interest in this matter. The representatives are committed to make community engagement a core function of their institutions and we all agreed that we should get more involved in expanding this across all institutions. A need for a formal structure for us all to work together and have a more collective voice was also identified,” said Rev Kiepie Jaftha, Chief Director: Community Service at the UFS and Chairperson of the NatCEMF Steering Committee.

“There is a growing need to expand and develop our engagement with communities – to share our experiences and best practices and to learn from each other. There are universities that are doing excellent work in this field and, by having a formal structure, we can do a lot more towards advancing community engagement,” said Rev Jaftha.

The meeting identified matters such as the coordination of higher education institutions’ involvement in community engagement, the facilitation of research about community engagement, promoting service learning as transformation, the establishment of a community engagement resource centre and the organisation of a national community engagement conference as some of its aims. A national steering committee was also elected.

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