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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS academic leaves for national parliament
2009-05-28

The Head of the Department of Afro-asiatic Studies, Sign Language and Language Practice at the University of the Free State (UFS), Prof Annelie Lotriet (pictured), is leaving the university at the end of this month.

Prof Lotriet has been seconded to the national parliament as a member of the Democratic Alliance’s shadow cabinet responsible for arts and culture.

“I am very sad to go because I think I am leaving the university at a point where there are many changes coming and I think we are going to go into a very interesting and challenging time at this university with our new rector taking office one of these days,” she said.

“On that point I am actually sad that I am not going to be here to experience it because I think the university has all the potential to become one of the main role players in higher education in South Africa and, obviously, I will be watching it with interest.”

Prof Lotriet has worked for the UFS for 25 years and regards language and multilingualism as her passion. She reflected on her major achievement: “I think what still stands out for me was the fact that we ran the interpreting service for the Truth and Reconciliation Commission and that made an indelible impact on my life. We were involved in it right from the start to the end. We really put interpreting on the map.”

Mr Philemon Akach, a senior lecturer in the department, will act in her position until the end of the year.

“I have full confidence in him,” she said. “He is a world-renowned expert in interpreting and sign language, so I think the department is in good hands.”

Media Release:
Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt.stg@ufs.ac.za
28 May 2009




 

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