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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Golden Key Chapter of the UFS walks away with gold status
2011-10-13

 

This generation has to find a mission, something they can be as passionate about as their predecessors of the 1970s were. A greater nation has just risen. At the 2011 South African Golden Key Summit, were from left: Mr Ruddy Banyini, outgoing President: UFS Chapter; Mr Puso Thahane, President: Wits Chapter, and Mr Katleho Mohono, Vice-President (Internal): Wits Chapter.
Photo: Leonie Bolleurs

Our university earned gold status as one of the top chapters in the country. This was one of four awards won by the UFS at the 2011 South African Golden Key Summit held at the Bloemfontein Campus from 6-8 October 2011.

Mr Ruddy Banyini, outgoing  Golden Key president (UFS) and the president of the Wits Chapter jointly received the Regional Student Leader of the Year award. The UFS Chapter also took third place for Best Community Service as well as for Best Campus Awareness Initiative. This follows hot on the heels of the chapter winning the Golden Key International Chapter Service Award for the second consecutive year in May 2011.
 
The summit also yielded some new challenges for all chapters. Mr Banyini and his counterparts from the University of Witwatersrand are on a mission to cultivate a nation of thinkers. This follows the successful hosting of a Thinkers Symposium by the Wits Chapter to determine the contribution thinkers could make towards shaping a better society. “This initiative will see all students on campus mobilised and actively participating,” Mr Banyini said. “Thoughts without action are just thoughts. We are all aware of social ills in our country, yet only a few come forth with a solution,” stated Mr Katleho Mohono (Wits).
 
The involvement of Golden Key members in helping to create solutions for national problems has triggered a series of think-tank symposiums organised by various chapters. The result has been an exponential growth in the numbers of those collectively involved in the on-line National Planning Commission’s consultative forum. “The impact of mobilising the best current academic achievers in Higher Education opens up exciting new possibilities through constructive student engagement with society’s issues,” Dr Derek Swemmer, Registrar at the UFS,” said.

 

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