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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Law Faculty to host symposium on corruption in the public sector
2014-06-03

Programme of symposium (pdf)

The Centre of Business Law at the UFS’s Faculty of Law will host a symposium on corruption with specific focus on the public sector.

The theme for this year’s symposium stemmed from the National Planning Commission’s emphasis on strengthening accountability and fighting corruption in South Africa. This was identified as a priority and a critical action area in the National Development Plan of 2011.

The Public Protector of South Africa, Adv Thuli Madonsela, will deliver the keynote address. Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, will deliver the opening address.

Other high-profile speakers to appear at this event are:

• The Honourable Mr Justice FDJ Brand, Judge of the Supreme Court of Appeal of the Republic of South Africa;
• The Honourable Mr Justice SPB Hancke, Judge of the Free State High Court;
• Prof JJ Henning, Distinguished Professor and Acting Dean of the Faculty of Law;
• The Honourable Mr Justice A Kruger, Judge of the Free State High Court;
• Dr Johan Burger, Senior Researcher, Crime and Justice Programme, Institute for Security Studies;
• Mr Willie Hofmeyr, Deputy National Director of Public Prosecutions, South Africa and Head of Asset Forfeiture Unit; and
• Mr Mzilikazi wa Afrika, Journalist at the Sunday Times investigations unit.

Date: Thursday 5 June 2014
Venue: CR Swart Auditorium, Bloemfontein Campus
Time: 08:30-16:00
RSVP: Dr  Adri du Plessis by duplessisa@ufs.ac.za

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