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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

2015 Open Day on Bloemfontein Campus inspires prospective students
2015-05-14

Photo: Charl Devenish

“Here we use our minds and not muscles. We use reason and not rage.”

This is how Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), described what being a Kovsie is.

Prof Jansen welcomed thousands of prospective students and their parents to the Bloemfontein Campus on Saturday 9 May 2015 for the annual Open Day.

“Academics are everything. We don’t expect you to do well. We expect you to excel,” he said.

Prospective students got a taste of the #KovsieFeeling with a mind-dazzling laser show, a surprise performance by Micasa, the introduction of our sports champions, and an inspiring message from our SRC President, Mosa Leteane.

“When you are comfortable, you are not challenged. You can only learn to grow when you are uncomfortable.”

Visitors also had first-hand experience of how accessible Prof Jansen really is. At the Talk to Me gazebo outside his office, Prof Jansen dished up food while having a chat with parents. This gesture echoed Prof Jansen’s message: “If you want to be a decent human being, welcome to Kovsies.”

To all its visitors, the 2015 Kovsie Open Day, with all its fun and laughter, reflected the truth of the UFS as an academic institution that inspires excellence and transforms lives.

Even if you missed the Kovsie Open Day, be sure to grab the chance to study at our university, and ensure a lifetime of excellence and innovation. You can visit our Prospective Student webpage for more information.

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