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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

A hat trick for Kovsie Master’s student
2016-07-28

Description: Candice Thikeson  Tags: Candice Thikeson

Candice Thikeson from the University of the Free State
was the successful recipient of the Abe Bailey
Travel Bursary.
Photo: Johan Roux

Mandela Rhodes Scholar, Bright Young Mind, and now successful candidate of the Abe Bailey Travel Bursary. These accolades now all belong to Candice Thikeson from the University of the Free State (UFS).

To complete the hat trick, she was declared the recipient of the bursary on 20 July 2016. She follows in the footsteps of Stefan van der Westhuizen, who was the UFS Abe Bailey recipient in 2015.

An unexpected breakfast announcement

Thikeson, Gosego Moroka, and Wonga Mfana were the UFS final candidates for the bursary.

Thikeson, who is currently a Master’s student in Art History and Image Studies, said she never expected to be the successful candidate, but is really grateful. “I would like to thank the Vice-Chancellor and Rector, Prof Jonathan Jansen, the Dean of the Faculty of the Humanities, Prof Lucius Botes, and members of the Rectorate, and academic staff who gave me the news in such a special way.”

Promoting South African unity abroad

The objective of the bursary is to broaden the views of young South Africans to effect greater understanding and co-operation among those from various language and cultural backgrounds. Furthermore, it wants to empower those who show exceptional leadership qualities and a strong service ethic, while adopting commitment and effective participation in a common future.

Most importantly, the bursary seeks to promote South African unity. It is awarded each year and consists of a three-week educational tour of England and Scotland. The host in the United Kingdom will be Goodenough College in London.

Thikeson will be overseas from 22 November to 17 December 2016, visiting London, Cambridge, Oxford in the United Kingdom, and Edinburgh in Scotland.

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