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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

From Architecture graduate to fashion sensation
2016-11-14

Description:Paul Whitehead  Tags: Paul Whitehead  longdesc=

Paul Whitehead, owner and founder of
Major John.
Photo: Supplied

Paul Whitehead never thought the small business he started in his hostel room at the University of the Free State (UFS) in Huis Abraham Fischer on the Bloemfontein Campus would develop into something of magnitude.

Paul, who completed his Honours degree in Architecture in 2015 at the UFS, is currently taking a gap year due to the rapid growth of his business. Major John started back in December 2012, with Love Warrior becoming Paul’s first outlet. In 2014 Paul started manufacturing his first series of timber bow ties and after that, sales started booming.

Supplier to 16 outlets in South Africa

“We currently supply 16 outlets throughout South Africa with a range of products such as timber bow ties, genuine leather suspenders and concrete and timber desk lamps, as well as other leather products,” Paul says.

He says that a new range of nine timber bow ties is launched every four months. “The timber is recycled and the fabric is handpicked from around the country to ensure quality, thus the bow ties are hand-crafted and unique,” Paul says.

Trust your gut feeling and believe in yourself

His main goal with the timber bow ties is to expand while the unique quality of the product is not compromised. “We are also in a process of expanding the range of our products in the exclusive market.”

Paul attributes his success to delivering excellent service to people who appreciate his pride and joy, his Major John collection. He encourages future entrepreneurs to listen to others’ advice, but to trust their own gut feeling and always believe in themselves.

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