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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Sello, Brits and Van Vuuren shine at Varsity athletics
2017-03-10

Description:Varsity athletics   Tags: Varsity athletics  longdesc=

Elmé Smith represented Kovsies in the 100 m
and 200 m at the Varsity athletics event in
Potchefstroom.
Photo: Mario van de Wall/SASPA

Jovan van Vuuren, Maryke Brits, and Tsepang Sello were our big stars at the first Varsity athletics event in Potchefstroom. They all finished first in their items and helped their Kovsies team claim an excellent overall third position among eight universities.

The jumps by Van Vuuren and Brits (both long jump) of 7.73 m and 6.11 m respectively were the longest, while Sello’s time in the 800 m was 2:12.01. Brits not only won the long jump, but was also second in the 100 m hurdles (13.65 s).

UFS outperform the likes of Maties, UJ

The Kovsies eventually bragged with three first, seven second, and two third spots on the podium. They ran, jumped and threw, bagging altogether 12 podium spots to accumulate 14 902 points (with an average of 993). Tuks, with 15 604 (1 040), and Pukke with 15 252 (1 017) was respectively first and second on 3 March 2017. Our team outperformed universities like the Maties and the University of Johannesburg.

Rynardt, Kesa claim second place

Big names such as Rynardt van Rensburg (800 m, second in 1:50.49) and Kesa Molotsane (1 500 m, second in 04:29.31) also scored podium spots. The second Varsity athletics meeting will take place in Pretoria on 31 March 2017.

Team results in Potch:

1. Tuks 15 604 (Top 15’s average: 1 040)
2. Puk 15 252 (1 017)
3. Kovsies 14 902 (993)
4. UJ 14857 (990)
5. Maties 14317 (954)
6. UWC 14068 (938)
7. Madibaz 13721 (915)
8. TUT 13463 (898)

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