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AEVGI advances Next-Generation Sequencing in Africa
Prof George Armah, Noguchi Memorial Institute for Medical Research, Ghana; Prof Carl Kirkwood, Bill and Melinda Gates Foundation, USA; Cornelius Hagenmeier, Director: Internationalisation, UFS; Prof Gert van Zyl, Dean: Health Sciences; Dr Martin Nyaga, Senior Lecturer in the NGS Unit; Prof Joyce Tsoka-Gwegweni, Vice-Dean: Health Sciences; Dr Glen Taylor, Senior Director: Research and Development; Prof Jeffrey Mphahlele, Vice-President, South African Medical Research Council.

The inaugural edition of the University of the Free State (UFS) Next-Generation Sequencing (NGS) Data and Bioinformatics Workshop, hosted by the UFS-NGS Unit in the UFS Faculty of Health Sciences, marked a new beginning for the advancement of NGS in Africa under the auspices of the African Enteric Viruses Genome Initiative (AEVGI), which was recently funded by the Bill and Melinda Gates Foundation.

The AEVGI will generate rotavirus genomes at the UFS-NGS Unit to investigate the long-term effects of the introduction of the monovalent RV1 vaccine in three African countries – Ghana, Malawi, and South Africa.

The workshop attracted over 90 participants from 15 national and international institutions, with organisations from seven different countries as well as company representatives attending the event. The workshop kicked off with a courtesy call to the Rector and Vice-Chancellor, Prof Francis Petersen, followed by a stakeholder meeting with the executive management of the UFS.

The funding was secured through an award to the principal investigator, Dr Martin Nyaga, and sub-awards to co-investigators, Dr Khuzwayo Jere, Dr Francis Dennis, and Dr Valentine Ndze. According to attendee evaluations of the workshop, the remarkable performance of the workshop instructors was outstanding. Through practical sessions, participants were equipped with knowledge on how to apply several tools of genetic data analysis, using the rotavirus genome as a model to construct and interpret different genomic datasets.

A total of 65 students attended the hands-on workshop, the majority of which were from South African higher-education institutions. The organisers are grateful to the sponsors, particularly to the Bill and Melinda Gates Foundation and the University of the Free State, for making the workshop a success. Whitehead Scientific and the South African Medical Research Council also played a major role in the success of the workshop. The local organising committee consisted of Dr Martin Nyaga (host, convener and chair), Dr Saheed Sabiu (secretary), and Mr Stephanus Riekert (principal ICT support).

News Archive

Most read articles in international journal authored by UFS academics
2011-10-06

 

Prof. James du Preez, Senior Professor and Head of the Department of Microbial, Biochemical and Food Biotechnology, and Prof. Lodewyk Kock, Outstanding Professor in the same department.
Photo: Leonie Bolleurs

FEMS Yeast Research, the top international journal in this field of research, recently announced their three "most read articles" of 2011, based on the number of downloads from their website. Of these three published papers, two are from the Department of Microbial, Biochemical and Food Biotechnology at the University of the Free State (UFS). They are:

The article with the title, The yeast Saccharomyces cerevisiae – the main character in beer brewing, was authored by Prof. Bettie Lodolo and Mr Martin Brooks (Brewing Consultant and Chief Brewer of the SAB Ltd. Brewing Centre of Excellence in Alrode, Johannesburg, respectively), Prof. Lodewyk Kock (Outstanding Professor in the UFS Department of Microbial, Biochemical and Food Biotechnology) and Prof. Barry Axcell (Global Chief Brewer, SABMiller, Sandton). Prof. Lodolo is also an Affiliated Professor in the UFS’s Department of Microbial, Biochemical and Food Biotechnology,

The authors of the second paper entitled The alcohol dehydrogenases of Saccharomyces cerevisiae: a comprehensive review, are Dr Olga de Smidt (Researcher at the Central University of Technology and a former Ph.D. student of the UFS Department of Microbial, Biochemical and Food Biotechnology); Prof. Koos Albertyn from the above department, and Prof. James du Preez Senior Professor and Head of this department.

The article by Lodolo et al. was also listed as one of the three most cited articles of 2010 published in this journal.

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