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06 July 2018 Photo Charl Devenish and Johan Roux
Prestigious academic medals awarded to outstanding UFS students
UFS Dean medal recipients top left; Sophia Pitcher, top right; HJ Prinsloo, centre; Lesley Jean Wright, bottom right; Mashudu Mathobo and Senate’s medal recipient bottom left; Enrico Scheltema at the 2018 June Graduation ceremonies.

During the recent June graduation ceremonies at the University of the Free State (UFS), the winter chill subsided with some heart-warming academic achievements in postgraduate studies. Four students were awarded a Dean’s medal for the best master’s degree in their respective faculties, and the overall best achiever received a Senate’s medal. The faculties in the limelight were Education, the Humanities, Theology and Religion, and Natural and Agricultural Sciences boasting both a Dean’s and Senate’s medal. 

Biblical analysis and interpretation
Interestingly, the Bible served as subject matter for two master’s degrees from two different faculties – each receiving a Dean’s medal. HJ Prinsloo, under the guidance of his study leader, Prof Francois Tolmie from the Faculty of Theology and Religion, took a closer look at Paul’s letter to the Galatians. “I hope that my studies made me become a critical-thinking theologian who can make a contribution to the interpretation of Paul’s letters,” Prinsloo said. He would like to continue his research by doing a PhD. “My academic interest is the rhetoric of the undisputed Pauline letters in the New Testament.” He gave all the glory and honour to God for his achievement. 

A few blocks down in the Faculty of the Humanities, Sophia Lynn Pitcher sunk her teeth into the Masoretic cantillation accents of the Hebrew Bible a complex medieval notation for recording the chanting and recitation of the Old Testament text. “Her prosodic model is ground-breaking in that it provides the key to unlocking the intonational patterns of the Old Testament, which will have significant implications for biblical interpretation and exegesis for Bible translators and students,” said her study leader, Prof Jacobus Naude, and co-study leader, Prof Cynthia Miller-Naude. “The study of the Masoretic accents has been largely ignored by Hebrew and biblical scholars,” they elaborated. “Her research demonstrates that it is possible to understand the Old Testament in light of the sounds of its sentences, as well as the words on the written page.”

Class time
In her striking polka-dot, ankle-high laced-up sneakers, Lesley Jean Wright not only earned her master’s degree with specialisation in Psychology of Education, but also the Dean’s Medal in the Faculty of Education. Although she has always been an achiever, it was the first time that she received an award of this calibre at university level. “My research is part of the way in which I have chosen to change the world in which I live,” she explains her passion and drive. “The best part of my studies was learning in so much more depth about an area of which I knew very little in academic terms.” She completed her research titled, A Collaborative Inquiry Towards Understanding the Experiences of ‘Out’ Lesbian and Gay Teachers in Gauteng Schools, under the guidance of her supervisor and mentor, Prof Dennis Francis from Stellenbosch University

Maths minds

The Faculty of Natural and Agricultural Sciences had a proud moment when two of their students received sought-after awards. “Modelling real-world problems with mathematical tools is perhaps one of the most difficult exercises in research,” said Prof Abdon Atangana about the research of his student, Mashudu Mathobo, who received a Dean’s medal. Prof Atangana commended Mathobo’s passion, devotion, and dedication to his studies. “He was at my door every morning to discuss the previous night’s work.” Mathobo revised Theis’s mathematical model portraying the movement of groundwater to find a more accurate solution. He came up with an exact groundwater flow equation for a confined aquifer, taking all Theis’s assumptions into account, as well as high-order terms that Theis removed from his equation. 

Also using mathematics to solve problems of a different kind, was Actuarial Science student and Senate’s medal recipient, Enrico Scheltema. Currently in his honours year, he received this noteworthy award for his undergraduate studies. He is driven by his love for problem-solving and is looking forward to entering the workplace next year. “It is an interesting feeling to be awarded for something you did some time ago,” Scheltema said. While he is yet to fully appreciate the magnificence of his achievement, the faculty and university salutes the young man for his brilliance and dedication.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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