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12 March 2018 Photo Leonie Bolleurs
Second triumph for young pollution and pharmaceutical researcher
Emmie Chiyindiko, winner of Famelab.

“I am grateful to be reaping the benefits of stepping out of my comfort zone. By facing the unfamiliar, that challenge will allow me to see what great things I am capable of,” said Emmie Chiyindiko, winner of Famelab 2018.

With FameLab, the world’s leading science communication competition, participants have just three minutes to win over the judges and crowd with a scientific talk that excels in content, clarity and charisma. Contestants from around the world participate, armed only with their wits and a few props.

Emmie won the Postgraduate School’s Three-Minute-Thesis competition for master’s level in 2017.

She said: “My research is based on the synthesis and characterisation of a series of unique metal complexes.” These complexes are used both as active pharmaceutical ingredients and cosmetic additives to reduce the detrimental effects of UV radiation on the skin. They are incorporated into anti-ulcer, gastro protective drugs, anti-asthmatic, lung disease drugs, with anti-cancer and anti-diabetic agents,” she said.

With her research she can also monitor air pollution. Formaldehyde is a known toxin to human health. “Using metal complexes, I am able to monitor the production of formaldehyde and consequently come up with exposure prevention methods,” said Emmie.

She believes that it is okay to not ”fit in“. “Mannerisms such as your quirks make you different and distinctive. Live your life intentionally, imprint your personal mark on this universe and always choose faith over fear.”

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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