Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
19 March 2018 | Story Eugene Seegers | Photo Charl Devenish
UFS collaborates with Wits UWC to present higher education PhD Conference
Prof Merridy Wilson-Strydom (UFS, Prof Patricio Langa (UWC), Prof Melanie Walker (UFS), and Prof Stephanie Allais (Wits) at the keynote address delivered by Prof Allais.

The higher education sector in Africa has seen dramatic shifts over the past few years, and has attracted renewed attention from global funders and national policy-makers. In turn, country-wide challenges of poverty, inequalities, and university histories and stratification in South Africa and elsewhere on the continent offer rich opportunities for critical, theoretically-informed research to investigate and understand the conditions of possibility for change nationally and comparatively.

In particular, three centres at universities in South Africa have decided to build an organic collaboration, starting with research by doctoral research fellows at these universities, who presented papers at a two-day conference. The conference was jointly organised and hosted under the umbrella of the SARCHi (South African Research Chairs Initiative) Chair in Higher Education and Human Development at the Bloemfontein Campus of University of the Free State (UFS). Two keynote addresses on significant issues in the sector were presented by Prof Stephanie Allais, Director of the Centre for Researching Education and Labour (REAL, University of the Witwatersrand) and Prof Patricio Langa, Associate Professor of Sociology and Higher Education Studies at the Institute for Post-School Studies (IPPS, University of the Western Cape).

HE researchers collaborate
This ongoing collaboration between the three universities was initiated by Prof Melanie Walker at the UFS, in partnership with Prof Allais and Prof Langa and their institutions, with each institution taking a turn to host similar conferences. The conference at the UFS not only brought together doctoral researchers from these three centres to share their research, but it also offered the opportunity to engage with other early-career and experienced scholars. 

The conference was themed Critical Higher Education Studies: Theories and Research and aimed to build research relationships and stimulate debate among scholars. It was jointly organised by postdoctoral fellows: Ntimi Mtawa and Faith Mkwananzi (UFS), Bothwell Manyonga (Wits), and Patrick Swanzy (UWC).

Significant benefits for conference-goers and presenters alike

Conference-goers, as well as the presenters, reported great benefits as a result of their attendance and participation in the event. The research papers were important and central. However, the broader value of the conference was the platform it offered to young, emerging scholars to showcase their research projects, receive critical comments, listen and learn from one another, in addition to engaging with experienced scholars. 

Secondly, the variety of PhD research fellows who presented their research further enhanced critical academic engagement and the exchange of ideas. Presenters reported that the quality of feedback and comments on their projects had especially enhanced their current work. The focus of the stimulating keynote addresses also challenged participants to think well and critically about the field of higher education. Practical skills development also featured on the programme in the form of learning how to present a TED-style talk.

“The conference was especially valuable in bringing together early-career researchers working on critical and theorised approaches to higher education,” said Prof Walker. She added, “In particular, I valued the diversity of both the projects and their theoretical frames, which proved especially rich, together with the outstanding keynote contributions—one from political economy and one from sociology—which shaped the event as a whole.”

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept