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31 May 2018 Photo Anja Aucamp
Microbiology department receives Research Chair in Pathogenic Yeasts Prof Carlien Pohl-Albertyn
Prof Carlien Pohl-Albertyn, Professor in the Department of Microbial, Biochemical and Food Biotechnology


The National Research Foundation (NRF) recently approved a fifth research chair for the University of the Free State (UFS), the Research Chair in Pathogenic Yeasts. Prof Carlien Pohl-Albertyn from the Department of Microbial, Biochemical and Food Biotechnology, will be chairing this research chair. 

Activities of the Research Chair in Pathogenic Yeasts builds on existing research strengths and will contribute towards understanding pathobiology of medically significant pathogenic yeasts belonging to the genera Candida and Cryptococcus. 

According to Prof Pohl-Albertyn, the research group, established in 2014, is the only one in South African focusing on understanding the role of bioactive lipids in host-pathogen interaction as well as in the search for novel drug targets. The group brought together three principal investigators, Prof Pohl-Albertyn, Prof Koos Albertyn and Dr Olihile Sebolai, with knowledge regarding various virulence factors (including immunomodulatory metabolites) produced by the Candida and Cryptococcus as well as molecular biology of yeasts. Besides the three principal investigators, the group also includes five PhD students, nine MSc students, four BSc honours students as well as two postdoctoral fellows. 

Current projects of the group include the production of immunomodulatory compounds by the yeasts, finding novel targets for antifungal drugs and the interaction between the yeasts and different hosts using a variety of infection models. In addition, the interaction between pathogenic yeasts and other co-infecting pathogens is also being investigated. 

Why research on fungal infections?
“As a result of presently used treatments for diseases and HIV/Aids, and the advances in medical interventions, many diseases no longer pose a threat to humans and life expectancy is prolonged. However, this has also caused an increase in various opportunistic infections, and most of all, fungal infections.

“With an increase in the number of individuals sensitive to invasive fungal infections, yeasts have begun to be reported more frequently as pathogens (yeasts that can cause disease). Infections by pathogenic yeasts affect a wide variety of patients. Although most of them are immunosuppressed (including HIV positive) other underlying conditions may predispose people to such infections. These include extremes of age (premature infants and the elderly), diabetes, cancer and cystic fibroses. In addition, patients hospitalised in intensive care units, as well as patients undergoing major abdominal or thoracic surgery are at high risk of invasive candidiasis. Similarly, HIV/Aids, liver cirrhosis and immunosuppressive therapy are known risk factors for invasive cryptococcosis,” said Prof Pohl-Albertyn.

According to her an important hurdle in the treatment of invasive yeast infection is the emergence of drug resistance in these pathogens. Therefore, research into pathobiology, including new drug targets, as well as novel treatment options, is a necessity. 

In line with the UFS research strategy
The NRF call for research chairs, specifically aimed at female researchers at universities that currently have fewer than 15 research chairs, came out in May 2017.

The university considers the current SARChi Chairs and the possibility of future chairs as an integral and strategic initiative to increase its national and international standing through excellent academic and research leadership. A Research Chair in Pathogenic Yeasts is therefore an invaluable addition to the UFS Research Strategy. 

The Research Chair is for five years, and is renewable for three terms.

Microbiology from University of the Free State on Vimeo.

News Archive

Quantity Surveying and Construction Management department aspires to excellence
2017-08-14

Description: Prof Kahilu Kajimo-Shakantu Tags: Prof Kahilu Kajimo-Shakantu 

From the left: Prof Danie Vermeulen, Dean of the
Faculty of Natural and Agricultural Sciences;
Prof Kahilu Kajimo-Shakantu, Head of the Department
of Quantity Surveying and Construction Management;
Prof Francis Petersen, Rector and Vice-Chancellor
at the UFS; and Dr Franco Geminiani, chairing the
panel from the South African Council for the Project
and Construction Management Professions.
Photo: Leonie Bolleurs

Achieving programme accreditation from the respective professional bodies is the ultimate goal for the Department of Quantity Surveying and Construction Management at the University of the Free State (UFS). This is according to Prof Kahilu Kajimo-Shakantu, the head of this department. This hallmark of quality reflects the university’s aspiration towards excellence.

Construction Management programmes reviewed
The university recently received a visit by a panel, representing the South African Council for the Project and Construction Management Professions (SACPCMP) to re-accredit programmes offered by the Department of Quantity Surveying and Construction Management. During the accreditation visit, the panel evaluated the programmes to determine whether they met the minimum requirements according to a set of pre-determined criteria.

When reviewing the programmes: BSc and BSc Hons Construction Management respectively, as well as the Project Management stream of the Masters programme in Land and Property Development Management (MLPM), the panel looked at programme design and outcomes including curriculum, study material and exam papers, institutional support, student recruitment, admission, development, retention and throughput, staffing recruitment and development, teaching and learning strategies, quality assurance, facilities, infrastructure and resources, professional development, industry and practical exposure and postgraduate policies, procedures and regulations, including research activities.

If the minimum requirements are achieved, the Department of Quantity Surveying and Construction Management at the UFS will receive accreditation for its programmes from 1 April 2017 to 31 March 2022.

It will also mean that we are certified
as producing quality employable
graduates who are well prepared to
enter the industry and make a difference.

Currently, the department has full accreditation by the SACPCMP (until March 2017) and the SACQSP (until December 2017).

Later this month, a panel from the South African Council for Property Valuation Profession (SACPVP) will review the accreditation of the Valuation stream of the MLPM programme. The South African Council for Quantity Surveying Profession responsible for accrediting the Quantity Surveying programmes will visit the university in 2018.

Certified as producing quality students

Prof Kajimo-Shakantu said: “If we maintain our accreditation, it will reflect that the UFS is among the best, with programmes which are recognised by professional bodies that set competence standards for professional registration of students. It will also mean that we are certified as producing quality employable graduates who are well prepared to enter the industry and make a difference. The programmes contribute to the development of the much-needed critical skills in the built environment.”


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