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17 September 2018
Photo Charl Devenish
Innocensia Mangoato’s research on using cannabis to reverse anticancer drug resistance has been awarded in the prestigious Women in Science Awards.
“There’s this misconception among young people that science is difficult and that it’s somehow a man’s domain,” says Innocensia Mangoato, Masters student in Pharmacology, who has just been awarded in the prestigious Women in Science Awards by the Department of Science and Technology.
Cannabis research
Innocensia won in the Master’s Degree category for her research on the use of cannabis in reversing anticancer drug resistance. Her department had to apply for a special permit to grow cannabis for research and medicinal purposes.
“Her findings have already indicated a promising reversal of resistance to drugs in a variety of cancers. We plan to explore these results further in a possible PhD,” says her study leader, Prof Motlalepula Matsabisa.
Innocensia says she’s always had an interest in science, and initially wanted to study medicine. She ended up doing a BSc in Physiology and Genetics.
She hopes that her research will help government to develop a policy around the use of cannabis for medicinal purposes which could ultimately lead to developing cancer treatment with fewer side-effects.
Female mentors
“My mentor during my Honours studies was Dr Makhotso Lekhoa. Her passion for her field and her patience in conveying it to others really inspired me. We have some very powerful women in our Pharmacology Department,” says Innocensia.
Passion for science
“You know you’re passionate about your work when you find yourself going to the lab on Sunday afternoons!” she says. “I’m happy that I can be contributing to the knowledge production on this campus. And maybe one day I can be a mentor to other girls with that same passion for science.”
#Women'sMonth: Lack of HIV education still affects children
2017-08-17
Dr Nickie Goedhals, Senior Lecturer and Pathologist
in Medical Microbiology and Virology at the UFS.
Photo: Sonia Small
“Despite all the advances in the management and prevention of HIV, children still become infected every day, often due to lack of education and access to health care.” This is according to Dr Nickie Goedhals, Senior Lecturer and Pathologist in Medical Microbiology and Virology at the University of the Free State (UFS).
Study published in UK medical Journal
A case study she was part of and published in the UK medical journal The Lancet in 2012, demonstrates the transmission of HIV to a child through surrogate breastfeeding. This study is one of the many highlights in the young researcher’s career. She received her first rating from the National Research Foundation (NRF) in 2017 for the work she has done in Medical Virology over the past eight years.
According to the above-mentioned study, only about 1% of infants in South Africa are being breastfed by a surrogate. However, results from a study in the Free State showed that shared breastfeeding by a non-biological caregiver was the most important factor associated with HIV infection in discordant mother-child pairs. Therefore, continued education about the risk of HIV transmission is needed.
Dr Goedhals is also continuing with research on HIV by looking at HIV drug resistance. She is in the process of starting new projects focusing on HIV infection and drug resistance in infants.
PSP helped with NRF-rating
She says, although her NRF Y2-rating is the starting point of a research career, it shows that she is heading in the right direction, and it “gives access to research funds through the NRF for future projects.” Other important research she conducted was on Crimean-Congo haemorrhagic fever – the study for her PhD.
The Prestige Scholars Programme (PSP) at the UFS is the reason that she applied for the rating. “With all the service delivery, teaching, and administrative responsibilities of academic medicine, it is easy to lose focus. The PSP has really helped to create a focused and stimulating environment for research.” According to her, the PSP also provides access to a network of peers and senior staff at the UFS, as well as exposure to national and international experts.