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17 September 2018 Photo Charl Devenish
Science Its a girl thing
Innocensia Mangoato’s research on using cannabis to reverse anticancer drug resistance has been awarded in the prestigious Women in Science Awards.


“There’s this misconception among young people that science is difficult and that it’s somehow a man’s domain,” says Innocensia Mangoato, Masters student in Pharmacology, who has just been awarded in the prestigious Women in Science Awards by the Department of Science and Technology.

Cannabis research

Innocensia won in the Master’s Degree category for her research on the use of cannabis in reversing anticancer drug resistance. Her department had to apply for a special permit to grow cannabis for research and medicinal purposes.

“Her findings have already indicated a promising reversal of resistance to drugs in a variety of cancers. We plan to explore these results further in a possible PhD,” says her study leader, Prof Motlalepula Matsabisa.

Innocensia says she’s always had an interest in science, and initially wanted to study medicine. She ended up doing a BSc in Physiology and Genetics.

She hopes that her research will help government to develop a policy around the use of cannabis for medicinal purposes which could ultimately lead to developing cancer treatment with fewer side-effects.

Female mentors

“My mentor during my Honours studies was Dr Makhotso Lekhoa. Her passion for her field and her patience in conveying it to others really inspired me. We have some very powerful women in our Pharmacology Department,” says Innocensia.

Passion for science 

“You know you’re passionate about your work when you find yourself going to the lab on Sunday afternoons!” she says. “I’m happy that I can be contributing to the knowledge production on this campus. And maybe one day I can be a mentor to other girls with that same passion for science.”

News Archive

Water erosion research help determine future of dams
2017-03-07

Description: Dr Jay le Roux Tags: Dr Jay le Roux

Dr Jay le Roux, one of 31 new NRF-rated
researchers at the University of the Free State,
aims for a higher rating from the NRF.
Photo: Rulanzen Martin

“This rating will motivate me to do more research, to improve outcomes, and to aim for a higher C-rating.” This was the response of Dr Jay le Roux, who was recently graded as an Y2-rated researcher by the National Research Foundation (NRF).

Dr Le Roux, senior lecturer in the Department of Geography at the University of the Free State (UFS), is one of 31 new NRF-rated researchers at the UFS. “This grading will make it possible to focus on more specific research during field research and to come in contact with other experts. Researchers are graded on their potential or contribution in their respective fields,” he said.

Research assess different techniques
His research on water erosion risk in South Africa (SA) is a methodological framework with three hierarchal levels presented. It was done in collaboration with the University of Pretoria (UP), Water Research Commission, Department of Agriculture, Forestry and Fisheries, and recently Rhodes University and the Department of Environmental Affairs. Dr Le Roux was registered for 5 years at UP, while working full-time for the Agricultural Research Council – Institute for Soil, Climate and Water (ARC-ISCW).

Water erosion risk assessment in South Africa: towards a methodological framework
, illustrates the most feasible erosion assessment techniques and input datasets that can be used to map water erosion features in SA. It also emphasises the simplicity required for application at a regional scale, with proper incorporation of the most important erosion-causal factors.

The main feature that distinguishes this approach from previous studies is the fact that this study interprets erosion features as individual sediment sources. Modelling the sediment yield contribution from gully erosion (also known as dongas) with emphasis on connectivity and sediment transport, can be considered as an important step towards the assessment of sediment produce at regional scale. 
 
Dams a pivotal element in river networks

Soil is an important, but limited natural resource in SA. Soil erosion not only involves loss of fertile topsoil and reduction of soil productivity, but is also coupled with serious off-site impacts related to increased mobilisation of sediment and delivery to rivers.

The siltation of dams is a big problem in SA, especially dams that are located in eroded catchment areas. Dr Le Roux recently developed a model to assess sediment yield contribution from gully erosion at a large catchment scale. “The Mzimvubu River Catchment is the only large river network in SA on record without a dam.” The flow and sediment yield in the catchment made it possible to estimate dam life expectancies on between 43 and 55 years for future dams in the area.
 
Future model to assess soil erosion
“I plan to finalise a soil erosion model that will determine the sediment yield of gully erosion on a bigger scale.” It will be useful to determine the lifespan of dams where gully erosion is a big problem. Two of his PhD students are currently working on project proposals to assess soil erosion with the help of remote sensing techniques.

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