Latest News Archive

Please select Category, Year, and then Month to display items
Categories
UFS News Media Release Research
Years
2017 2018 2019 2020 2021 2022 2023 2024
Months
January February March April May June July August September October November December
Previous Archive
13 January 2020 | Story Eugene Seegers | Photo Anja Aucamp
New Way to learn a language
Spearheading the digital expansion of the conversational Sesotho course is IDEAS Lab Director, Johann Möller (middle). With him are from the left: Prof Pule Phindane, CUT; Dr Brenton Fredericks, CUT; Bahedile Letlala, UFS Department of African Languages; and Dr Elias Malete, UFS Department of African Languages.

For many years now, the UFS has been offering a one-year course in conversational Sesotho for staff members; this can then be followed up with the one-year course in advanced conversational Sesotho. The conversational Sesotho for students in the Faculty of Education was introduced in 2018 at the UFS.

The Central University of Technology (CUT) needed a conversational course for its first-year students and approached the Department of African Languages for the development of such a course. Living as we do in a multilingual country; this additional language skill opens doors and often hearts as well.


Using instructional design principles

However, the need was identified by both CUT and UFS to present this crucial information in a way that would be more appealing to digital natives as well as to those less familiar with technology. The Department of African Languages on the UFS Bloemfontein Campus, together with relevant departments from the CUT, approached the IDEAS Lab located on the UFS South Campus, since they already have a reputation for being a specialist on broadcasting and repackaging curricular content for digital presentations. The IDEAS Lab provided technical advice and built the multimedia programme, which will help the user to hear and practice phrases in Sesotho, using instructional design principles. The course will be available to both staff and students belonging to the two universities.

Room for growth

Johann Möller, Director of the IDEAS Lab, says this pilot programme will give both institutions the opportunity to test the use of multimedia for language acquisition. He adds, “Language is extremely complex, and we would like to expand this learning aid in the future.” In fact, the original design has room for growth built into it.

To keep things simple for the user and the building team, it was decided to start out with only four potential everyday scenarios where a staff member would like to speak Sesotho: Firstly, how to greet other persons from different genders; secondly, potential scenarios one might encounter in the university environment itself; thirdly, how to deal with situations at a hospital; and finally, how to use one’s language skills at a filling station.

Pronunciation is key

Each scenario contains three to four conversations that the learner can revise, along with images and audio that illustrate the situation and assist with correct pronunciation. The system does not allow the user to progress unless they have listened to the pronunciations of the sample sentences or phrases.

Further reading material and vocabulary lists are also provided, with the result that people who are using the programme can learn at their own pace. The authoring software Articulate Storyline was used to build the individual scenarios and each conversation or lesson within it. The lessons are also not dependent on an internet connection; they can be downloaded onto a flash memory drive and used offline.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept