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30 October 2020 | Story Leonie Bolleurs

The Department of Science and Technology has extended two of the National Research Foundation’s SARChI research chairs at the University of the Free State (UFS). 

The Research Chair in Diseases and Quality of Field Crops, together with the Research Chair in Vector-borne and Zoonotic Pathogens, have both been extended for another five years. 

Prof Maryke Labuschagne, currently Professor of Plant Breeding in the Department of Plant Sciences, is leading the chair on Diseases and Quality of Field Crops.

The Chair on Vector-borne and Zoonotic Pathogens is headed by Prof Felicity Burt from the Division of Virology in the Faculty of Health Sciences.

Prof Corli Witthuhn, Vice-Rector: Research, says it was the hard work and commitment of Profs Labuschagne and Burt that resulted in the extension of the SARChI research chairs. “They have excelled in terms of student supervision and publications in high-impact international journals.  They also serve as mentors for young academics, postdoctoral fellows, and colleagues through their passion for their different fields of interest.”

Prof Witthuhn believes that this extension of the two SARChI chairs speaks of the progress that the UFS has made in terms of developing itself as a research-led university. “We are proud of the two senior academics for their supervision, mentorship, and leadership and their contribution to building our reputation,” she says. 

Diseases and Quality of Field Crops

The focus of the research chair in Diseases and Quality of Field Crops is on advancing food security and nutrition in Africa and contributing to poverty reduction and achieving sustainability goals. 

Prof Labuschagne says despite recent advances, the headlines regarding hunger and food security remain alarming: one in nine people on earth will go to bed hungry every night. Globally, 800 million people do not have enough to eat to be healthy, and a third of all deaths among children under five in developing countries are linked to undernourishment. 

She believes the uniqueness and strength of the research chair lies in a two-pronged approach, namely the breeding of cereal crops for resistance to fungal diseases, and improving the quality of crops for processing and consumption, thus making an impact on food security in South Africa and the rest of Africa through this collaborative effort. 

She is confident that the extension of the research chair will allow them to continue and to expand their research, “which has built up a lot of momentum”.

Besides the 12 PhD and 8 MSc degrees they delivered in the first five years, they also contributed significant research outputs and cultivar releases. She adds that they would like to expand on the significant international collaboration they have established. 

Vector-borne and Zoonotic Pathogens

According to Prof Burt, the SARChI chair in Vector-borne and Zoonotic Pathogens builds on existing research strengths at the UFS and aims to contribute towards identifying and investigating medically significant arboviruses and zoonotic viruses in the country.
 
“To date, the research chair has facilitated progress towards establishing serosurveillance studies for various vector-borne viruses, specifically Crimean-Congo haemorrhagic fever virus, a tick-borne and zoonotic virus that causes severe disease with fatalities.”

The team of researchers operating within this research chair is currently also performing studies to determine the seroprevalence of severe acute respiratory coronavirus 2 (SARS-CoV-2) in the Free State.

Prof Burt has always taken the importance of community engagement into account, and with the current pandemic, she believes that it is now more important than ever to increase public awareness of zoonotic diseases.

She emphasises that the majority of new and emerging viruses are zoonotic in origin and that the current SARS-CoV-2 pandemic highlights the impact of an emerging zoonotic pathogen on society. Therefore, she feels that it is important to build capacity in this field and to focus research efforts on identifying and understanding where these pathogens cycle in nature, the potential for spill-over to humans, and what the drivers are for the emergence of these pathogens.

Prof Burt trusts that the renewal of the research chair will allow them to take advantage of the new biosafety laboratory that the UFS has invested in. “This will permit us to research pathogens that were previously excluded from our programme due to biosafety considerations.  The chair will furthermore contribute towards enhancing, strengthening, and developing research and knowledge in the field of epidemiology and pathogenesis of vector-borne and zoonotic viruses,” she says. 

News Archive

Haemophilia home infusion workshop
2017-12-17


 Description: haemophilia Tags: Haemophilia, community, patient, clinical skills, training 

Parents receive training for homecare of their children with haemophilia.
Photo Supplied


Caregivers for haemophilia patients, and patients themselves from around the Free State and Northern Cape attended a home infusion workshop held by the Clinical Skills unit in the Faculty of Health Sciences in July 2017. “It felt liberating and I feel confident to give the factor to my son correctly,” said Amanda Chaba-Okeke, the mother of a young patient, at the workshop. Her son, also at the workshop, agreed. “It felt lovely and good to learn how to administer factor VIII.” 

Clinical skills to empower parents and communities

There were two concurrent sessions: one attended by doctors from the Haemophilia Treatment Centre, and the other attended by community members including factor VIII and XI recipients, caregivers and parents. The doctors’ meeting was shown informative videos and demonstrations on how to administer the newly devised factor VII and XI kit, and discussed the pressing need for trained nurses at local clinics. Dr Jaco Joubert, a haematologist, made an educational presentation to the community members.

The South African Haemophilia Foundation was represented by Mahlomola Sewolane, who gave a brief talk about the role of the organisation in relation to the condition. Meanwhile, procedural training in the simulation laboratory involved doctors and nurses helping participants to learn the procedures by using mannequins and even some volunteers from among the patients.

A medical condition causing serious complications
Haemophilia is a medical condition in which the ability of the blood to clot is severely impaired, even from a slight injury. The condition is typically caused by a hereditary lack of a coagulation factor, most often factor VIII. Usually patients must go through replacement therapy in which concentrates of clotting factor VIII (for haemophilia A) or clotting factor IX (for haemophilia B) are slowly dripped or injected into the vein, to help replace the clotting factor that is missing or low. Patients have to receive this treatment in hospital.

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