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07 September 2020 | Story Prof Felicity Burt | Photo Supplied
Prof Felicity Burt in front of the new state-of-the-art biosafety Level (BSL) 3 laboratory.

The University of the Free State’s (UFS) new biosafety Level (BSL) 3 laboratory will allow the university’s world-respected researchers to further advance their research on and surveillance of infectious pathogens, with the ultimate benefit being the improved quality of health for the communities of the Free State and beyond.

That is the word from two leading UFS academics on the completion of the new facility; the BSL 3 laboratory will further enhance the university’s reputation for high-level international research – especially in the field of human pathogens – which will help to prevent disease and lead to better health outcomes.

The UFS Vice-Rector of Research, Professor Corli Witthuhn, stressed how important it is to have a facility of this nature – the only one of its kind in central South Africa – on the Bloemfontein campus, noting that its relevance is even greater, its role more critical now that the world finds itself in the grip of the global COVID-19 pandemic.

Intensify research of the impact on human pathogens

“The new BSL 3 facility – the Pathogen Research Laboratory – promises to intensify our research of the impact on human pathogens, as it allows our South African Research Chairs (SARChl) and other outstanding researchers to broaden the range of microbial pathogens that are being studied, and gain a better understanding of the global disease burden,” she said.

Her sentiments were echoed by the university’s Dean of the Faculty of Health Sciences, Prof Gert van Zyl, who added that the international level of quality research carried out in this facility will contribute to improvement in the disease profile of central South Africa.

“In supporting partners like the Free State Department of Health, this important scientific footprint in disease prevention and treatment will benefit the community at large by improving the quality of health research and delivering the best possible outcomes.”

The BSL 3 facility is supported by a small suite of laboratories for molecular and serological research and is accessible to any UFS researcher or student requiring a high level of pathogen containment. 

Appropriate biosafety and containment measures

Research and handling of infectious viruses and bacteria require appropriate biosafety and containment measures to prevent laboratory workers, personnel, and the environment being exposed to potentially biohazardous agents. 

There are four distinct levels of biosafety (levels one to four), with each having specific biosafety requirements. A BSL 3 laboratory is designed and precision-built to operate under negative pressure, and sees all exhausted air passing through a dedicated filter system to ensure that no pathogens escape into the environment. In addition, researchers wear appropriate personal protective equipment suited to the pathogens under investigation.  

The UFS BSL 3 laboratory is a modular container supplied by Air Filter Maintenance Services International (AFMS) and comprises two repurposed shipping containers. It was built and factory-tested in Johannesburg before being dismantled and relocated to the Bloemfontein Campus, where the containers were lifted by crane over trees and onto a concrete platform. The AFMS installation team then spent a number of days metamorphosing the two containers into a state-of-the-art laboratory, with a mechanical plant room and the ducting that maintains the laboratory under constant negative pressure, cleverly and discretely disguised behind cladding, allowing the structure to blend in with neighbouring buildings.

The need for training young researchers and developing skills

The Pathogen Research Laboratory is managed by Professor Felicity Burt, an arbovirologist with more than 25 years’ experience in handling infectious viruses. 

“Biosafety and biosecurity are essential in the investigation of emerging and infectious pathogens that cause significant disease and fatalities,” Prof Burt said.

“And while COVID-19, pandemic, viruses, vaccines, masks, social distancing, and lockdown were words seldom heard just six months ago, they are sadly now part of our everyday vocabulary,” she added, explaining that the current pandemic is the result of the zoonotic transmission of a virus from a wild animal to humans, with subsequent global spread.

“As this is not the first pandemic and will not be the last, the ongoing potential for the emergence of novel viruses and bacteria underscores the need for training young researchers and developing skills to tackle future outbreaks, develop new vaccines, understanding how pathogens cause disease, and discover alternate ways to mitigate outbreaks. 

“We are thrilled to have a state-of-the-art laboratory that allows us to safely handle those pathogens previously excluded from our research and surveillance programme. This facility positions the UFS to provide young scientists with world-class training and build capacity, now and into the future.”

* Division of Virology, University of the Free State, and NHLS, Bloemfontein, South Africa

News Archive

UFS council elects Nwaila and Hancke
2005-03-15

Dr Charles Nwaila, Superintendent-General of Education in the Free State, was elected Vice-chairperson of the UFS Council and Judge Faan Hancke was re-elected as Chairperson today.

According to the Rector and Vice-Chancellor, Prof Frederick Fourie, the election of Dr Nwaila is an important achievement for the UFS as Dr Nwaila is a well known leader in education in the Free State.

Dr Nwaila pledged to work constructively with the UFS council and management to ensure that the UFS benefits all people of the province and the country.

The appointments are valid for a term of three years from 1 June 2005 to 31 May 2008.

The elections took place at the quarterly meeting of the UFS Council where a number of other key transformation steps were approved.

The Council approved a Strategic Plan for the UFS which reflects a renewed focus on transformation of the institution, calling it an important roadmap for the future of the UFS.

According to Prof Fourie, the Strategic Plan tried strike a balance between continuity and change, addressing the need to remain an excellent university in an ever-changing context and environment.

Prof Fourie said transformation had many aspects and dimensions and could not be reduced to an issue of numbers.

The Strategic Plan identifies five strategic priorities and corresponding challenges in the next phase of transformation.

The priorities are:

  • quality and excellence

  • equity, diversity and redress

  • financial sustainability

  • regional co-operation and engagement.

  • outward thrust

Prof Fourie said that besides the five strategic priorities the plan also reflected concrete actions and interventions to address them.

He said the renewed focus on transformation is embedded in the priorities and specific actions that are identified.

The Council congratulated the management for the roadmap and for the achievements that have already been achieved in terms of transformation.

In order to draft a comprehensive Transformation Plan that will give substance to certain aspects of the UFS Strategic plan – or roadmap – the Council approved the establishment of a Transformation Plan Team.

The team will consist of about 16 people, which includes the two coordinators, Prof Teuns Verschoor, Vice-Rector: Academic Operations, and Dr Ezekiel Moraka, Vice-Rector: Student Affairs.

According to Prof Verschoor, the team was chosen and approved by the Executive Management earlier for the individual contributions that they could make.

While the individuals do not represent particular constituencies on campus they are a very diverse group of persons in terms of race, gender and various sections of the campus and the satellite campuses.

Prof Fourie, said there was an urgency and importance attached to the work of the Transformation Plan Team.

He said that while the team must produce a plan within a tight deadline, the task must be carried out very well, which could mean different stages in the work of the team.

According to the Rector, the UFS must take the lead in best practice transformation, while not underestimating the complexity of the issues facing the UFS.

The full list of names will be finalized soon.

MEDIA RELEASE
Issued by: Mnr Anton Fisher
Director: Strategic Communication
Cel: 072 207 8334
Tel: (051) 401-2749
11 Maart 2005

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