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28 September 2020 | Story Andre Damons | Photo Supplied
Dr Martin Nyaga, Senior Lecturer and Researcher: NGS, will be heading the World Health Organisation Collaborating Centre (WHO CC).

The University of the Free State (UFS) has been designated a World Health Organisation Collaborating Centre (WHO CC), and the university’s Next Generation Sequencing (NGS) Unit, in partnership with the World Health Organisation (WHO), will for the next four years be conducting genome sequencing of pathogenic organisms, including rotavirus strains from the African continent. 

This centre will be part of the Vaccine Preventable Diseases (VPD) Pathogens Genomics Cluster and will run from September 2020 to September 2024. 

Dr Martin Nyaga, Senior Lecturer and Researcher: NGS/Virology, who will be heading the WHO CC, says an institution is designated as a WHO CC by the WHO Director-General and endorsed by the host country’s minister of health to form part of an international collaborative network, carrying out activities in support of the WHO programmess at all levels. A designation as a WHO CC is a time-limited agreement of collaboration between WHO and the designated institution, through which the latter agrees to implement a series of concrete activities, specifically designed for WHO.

A supreme achievement

Says Dr Nyaga: “In my opinion, a WHO CC designation is one of the supreme achievements an institution can be conferred as a recognition for foregoing exceptional collaborative venture with the WHO and showing future potential to assist the WHO with its global programmes and in our case, the WHO Regional Office for Africa region to offer solutions to the WHO VPD Surveillance and pathogens genomics cluster.”

According to Dr Nyaga this designation was awarded to the UFS after the WHO was content with the outcome of a service contract whereby the UFS-NGS unit undertook a pilot rotavirus surveillance project at whole genome level, using two African countries for the pilot, Rwanda and Zambia.

“From the outcomes of the pilot surveillance project between 2017 and 2019, the WHO/AFRO was satisfied with the genomic data that was generated and partially disseminated in scientific databases and journals as a collaborative venture. 

“It was thus proposed to strengthen its existing collaboration with the UFS-NGS Unit, which initiated the application process to designate the UFS-NGS unit as a WHO CC, an initiative that has taken approximately 20 months to finalise through the different phases of the application and approvals for the designation,” explains Dr Nyaga.

The purpose of the WHO CC

The new WHO CC will upon request by the WHO, implement agreed work plans in a timely manner and to the highest possible standards of quality and must comply with the referred terms of reference and conditions. These include: 
• Conducting genome sequencing of pathogenic organisms causing VPD, including rotavirus strains collected as part of the routine VPD surveillance using NGS technology and analysis of the generated datasets using bioinformatics tools.

• Conducting molecular characterisation of specimens collected during outbreaks and public health emergencies as part of the support for monitoring, preparedness and response to VPD disease outbreaks in Africa.

• Provide technical guidance to WHO on strategies to improve laboratory molecular diagnostics, molecular typing and NGS of rotavirus diarrheal strains and other enteropathogens to detect novel and re-emerging strains. 

• Conduct validation of tools and new molecular diagnostics for detection and characterisation of unusual or rare VPD strains to guide studies and development of new vaccines for VPD.

• Organise capacity-building and training workshops on whole genome sequencing of priority VPD pathogenic organisms.

The impact of the WHO CC on the work of the UFS-NGS 

According to Dr Nyaga, the designation brings extra responsibilities to his work and to the activities of the UFS-NGS unit. “Such initiatives are very welcome to enhance the business aspects, research and academic activities of the UFS-NGS unit, as the benefits are quite holistic since the collaboration enhances co-ownership of data and offers opportunities to train postgraduate students and other scientists.

“It also expands the research infrastructure and most importantly contributes to policy for numerous African governments in important decisions such as vaccine implementation activities, from an informed point of view and managing public health needs that require rapid response like outbreaks that may lead to pandemics.” 
• The current WHO CC designations at South African Institutions of higher learning and research can be found at: 

News Archive

SA and Indonesia strengthen educational ties
2016-05-19

Description: Embassy of Indonesia  Tags: Embassy of Indonesia

From the left were Prof Hussein Solomon, Senior Professor at the Department of Political Studies and Governance; Professor Ikrar Nusa Bhakti, Research Professor of the Indonesian Institute of Sciences; Suprapto Martosetomo, ambassador of the Embassy of Indonesia to South Africa; and Prof Theodor Neethling, Head of the Department of Political Studies and Governance.
Photo: Johan Roux

“Indonesia and South Africa share one common trait which is diversity,” were the opening remarks of Suprapto Martosetomo, ambassador of the Embassy of Indonesia to South Africa. The ambassador drew parallels between the two republics at a public lecture hosted by the Department of Political Studies and Governance at the University of the Free State Bloemfontein Campus on 10 May 2016.

Professor Ikrar Nusa Bhakti, Research Professor in the Indonesian Institute of Sciences, presented the lecture on “Managing Political Diversities: The Indonesian Experience.” He outlined the history of Indonesia’s political and economic development, political system, and government’s policy in dealing with political and economic challenges, as well as the lessons learned from its experience.

Diversity and governance
As is South Africa, Indonesia is a ‘rainbow nation’. Being the largest country in the Southeast Asia, it boasts a population of approximately 250 million people, 300 ethnic groups, and 650 local languages. However, despite such diversity, the nation has been united behind the motto of “unity in diversity”, which was adopted when Indonesia proclaimed its independence in 1945.

Indonesia and SA also bear similarities in terms of a multiparty parliamentary system. Their current Joko Widodo and our Jacob Zuma administrations are governed by policies including anti-corruption, economic prosperity, equity and equality, quality education and healthcare, and maintenance of security.

International relations
The two countries have a long-standing relationship since 1955 when the Asia-Africa conference was held in Bandung, Indonesia. The conference represented solidarity against colonisation.

Prof Hussein Solomon, Senior Professor at the UFS Department of Political Studies and Governance, attributes Indonesia’s success as a product of education and leadership - something South Africa could learn from..“Indonesia like SA has been struggling with how to balance social diversity, democracy, and a political system. Despite this, they have managed to develop a functioning democracy and a vibrant economy. They are one of the top 20 economies in the world, and by the year 2035 will be in the top seven economies in the world, according to the Goldman Sachs, report,” he said.

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