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02 September 2020 | Story Andre Damons | Photo Supplied
Dr Satyajit Tripathy
Dr Satyajit Tripathy, a postdoctoral fellow from the Department of Pharmacology and Physiology, won the medal for the best oral performance at a UNESCO/UNITWIN network web seminar attended by more than 300 people from various institutions around the world.

A postdoctoral fellow in Pharmacology at the University of the Free State (UFS) was awarded a medal for the best oral e-poster presentation (Postdoctoral Fellow category) at a UNESCO/UNITWIN Network web seminar.

The two-day webinar with the theme Current concepts of Environmental Pollution by Electromagnetic field and Coronavirus was held in early August and was attended by more than 300 delegates from approximately 30 institutions from different countries.

Dr Satyajit Tripathy from the Department of Pharmacology won the medal for his outstanding research presentation on Employment of old options to control novel Coronavirus: Pros and Cons (authors: Barsha Dassarma, Satyajit Tripathy, MG Matsabisa). His presentations looked at immunotherapeutic techniques, such as the convalescent plasma (CP) therapy and possible diverse modes of action of the antimalarial drug hydroxychloroquine (HCQ) against COVID-19 infection.

The award will serve as motivation

He was excited to hear that he had won the award, says Dr Tripathy.

“I never thought I would win, but I tried my best. On the topic of possible modes of action of HCQ against the viral infection, we have published in the ‘International Journal of Antimicrobial Agents’ (S Tripathy, B Dassarma, H Chabalala, S Roy, and MG Matsabisa / International Journal of Antimicrobial Agents 56 (2020) 106028). All the authors are grateful to Prof Glen Taylor, Research Director at the UFS, and the UFS Department of Pharmacology, for giving us the opportunity,” says Dr Tripathy. 
According to him, receiving this award is a validation and boost to his confidence. “I am thankful to Prof Motlalepula Matsabisa (supervisor) and Dr Barsha Dassarma (my wife), who are also contributing actively to this project. Moreover, the award is a symbol of respect for my work and the acceptance of a greater responsibility to keep the UFS flag flying high.”
Dr Tripathy goes further to say that it will motivate him to work on HCQ or nano-HCQ delivery research on Coronaviruses. In his doctoral study, it has been found that chitosan-based nanochloroquine delivery increases antimalarial efficacy against rodent parasites. Against the Coronavirus, this type of approach might work to reduce the dose and increase the efficacy of HCQ, explains Dr Tripathy. 

Immediate saviour from the pandemic

In his presentation, Dr Tripathy argues that while the world is finding expedited approvals for the development of vaccines that are time-dependent, preventative, and possibly not a cure, physicians are considering the convalescent plasma (CP) therapy as an immediate saviour, and the antimalarial drug hydroxychloroquine (HCQ) as therapeutic options against COVID-19 infection, after assessing results from larger prospective, randomised, dose-determining controlled clinical trials. 
He concludes that, “Overall, in this situation of unavailability of specific medication, the CP therapy and HCQ treatment might act as an immediate saviour for society from the pandemic.”

News Archive

UFS team helps a pupil to hear again
2014-01-24

 

“I was scared at first. I could not remember the sound of my own voice. Being Deaf -it was like living on another planet.”

These are the words of the 18-year-old Andile (Godfrey) Jantjies after he heard sounds and words for the first time in almost 12 months.

Andile, a former pupil at the Albert Moroka School in Thaba Nchu, was the recipient of a cochlear implantation under the Bloemfontein Cochlear Implant Programme (BCIP) run by the Department of Otorhinolaryngology at the University of the Free State.

Andile lost his hearing after contracting bacterial meningitis in June 2013. This resulted in bilateral profound deafness and despite his good academic record, his school refused to have him enrolled for 2014.

The cochlear implant was inserted in October 2013 and was switched on for the first time on Thursday 23 January 2014.

“I want to go back immediately,” Andile said excitedly after gradually becoming comfortable with hearing his own and other voices.

Dr Iain Butler from the Department of Otorhinolaryngology says cases like Andile’s are a medical emergencies due to the fact that meningitis causes the inner ear to become replaced by bone.

“This can occur after as little as four months after the infection and means that the insertion of a cochlear implant becomes impossible.

A cochlear implant system costs approximately R220 000.

It converts sounds/speech into electrical signals that directly stimulate the auditory nerve, bypassing the damaged inner ear. It is indicated for babies with congenital hearing loss, as well as acquired hearing loss in children or adults. It requires intensive rehabilitation in order to learn to hear again, and most recipients develop very good hearing. Andile now has the opportunity to hear again, continue his schooling and become an economically independent member of society, rather than being dependent on others.

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