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Prof Motlalepula Matsabisa is Professor and Director of Pharmacology at the University of the Free State (UFS) and the chairperson of the World Health Organization’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

The Indigenous Knowledge System (IKS) for Health in the Department of Pharmacology in the Faculty of Health Sciences at the University of the Free State (UFS) has been awarded an annual Technology and Innovation Agency Platform (TIA) grant of R17 million for the next five years.

This research and teaching programme in the School of Clinical Medicine will now be rebranded and be known as the African Medicines Innovations and Technology Development Platform (AMITD), which will strive to respond to community health needs and address industry research challenges.

Prof Motlalepula Matsabisa, Professor and Director of Pharmacology, says the AMITD will aim to stimulate economic growth directly and indirectly by providing science-based solutions and developing technologies that utilise indigenous knowledge (IK) and South African iconic biodiversity to produce high-quality proprietary and commercial IKS/ African Traditional Medicine (ATM) products, focusing on priority diseases. 

Prof Matsabisa is also leading Africa’s fight against the COVID-19 pandemic after being appointed chairperson of the World Health Organization’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19 last year.
“Through this platform, IKS will be in a position to increase the number of postgraduate students being trained and developed in the fields of IKS health and pharmacology, technicians and technologists, scientists, researchers, and communities nationally and across our borders.”

“We will work with IK communities of practice in the field of health and traditional medical knowledge, together with the traditional health practitioners (THPs) in South Africa, encouraging them to participate meaningfully in the formal economy of the country by utilising the knowledge of the rich South African biodiversity. This will be done through an inclusive model, which will significantly empower the involved communities to become full participants in the formal economy,” says Prof Matsabisa. 

AMITD will answer industry needs and questions through technology development 

According to Prof Matsabisa, AMITD will work with private pharmaceutical companies to address technological challenges regarding herbal or ATM products that need improvement, and even develop new products for the market. The main scope of the platform will be to conduct applied and need-driven IKS health research.

The AMITD is envisaged to be a unique platform in that it will include focused technology development, community and indigenous knowledge-holder participation, inclusive innovation, bioprocessing, early commercialisation, and support. The focus will be on inclusive development and holistic research of IK-based products across the value chains, i.e., research, development, and commercialisation.  

Prof Matsabisa says the awarding of the IKS platform will see the UFS IKS compete favourably with other institutions globally. The UFS has declared the IKS as its flagship initiative and would like to advance IK-based innovation by transforming informal sectors into formal secondary economies that will be translated into actual decent job creation. 
“In the longer term, the plan is to establish an AMIDT Institute, and to become the international IKS research hub. To continue maintaining this position as the preferred research institute for training, research, and technology development for industry, government, local communities, and forming partnerships with leading national and international institutions.” 

“The overall benefits will be skills development, job and wealth creation at community level, high-level training at higher-education level, and industrial and business developments around IKS/ATM production activities. The AMIDT will move the country from the current resource-based thinking to a more intensive knowledge-based thinking and development.  Abundance of natural resources means nothing to the country if those resources cannot add value and develop commodities for industry development and job creation, including social impacts,” says Prof Matsabisa. 

Why IKS TIA platform for UFS

The UFS is recognised as a national leader in pharmacology as well as research and development of IKS and traditional medicines.  The UFS has developed and built infrastructure in this field of scientific research, and has the best modern equipment for the training, teaching, and development of prototypes and products for commercialisation based on IKS.  Interdisciplinary and interfaculty research is undertaken in this study area, and we have an excellent track record of sound community engagement with relevant stakeholders. 

“UFS pharmacology research is also recognised internationally as the science force in South Africa and Africa on IKS and traditional medicines research.  We have hosted and continue to host international students and researchers in our facilities and laboratories, which meet international scientific research standards and pharmaceutical manufacturing standards,” says Prof Matsabisa.     
 
The appointment of Pharmacology IKS as platform will further strengthen our current local, regional, and internationally active research collaborations.  These collaborations exemplify the strength and potential that the AMIDT platform could have in Asia, Africa, the UK, the US, Latin America, and Europe. We will strive to establish a mutually beneficial partnership with relevant players in Australia to make this a truly global IKS platform/research institute. 

The short-term goals of the platform are to

• create internationally competitive, quality, safe, effective, and easy-to-use products from local, commercially cultivated medicinal plants that consumers and patients have confidence in;
• develop and pilot locally developed technologies to meet local pharmaceutical needs;  
• create SANAS-accredited, standardised research methodologies on plant extraction, research, and validation;
• host students, technicians, technologists, researchers, and scientists (from South Africa, Africa, and abroad) to undertake short-term and long-term collaborative research;
• market the value of IKS to a competitive local industry and establish an ATM-based pharmaceutical industry in South Africa; and
• grow the platform through employment of qualified and competent personnel.

News Archive

UFS Chemistry wins dti award
2010-11-02

At the awards ceremony are, from the left: Director-General of Trade and Industry Mr Tshediso Matona, Prof. Andreas Roodt and the Deputy-Minister of Trade and Industry, Ms Bongi Maria Ntuli.
Photo: S Osman

The research group of Prof. Andreas Roodt, Head of the Department of Chemistry at the University of the Free State (UFS) in Bloemfontein, won the first prize in the category Development of Small Medium and Micro-Enterprises (SMME) at the annual Department of Trade and Industry’s (dti) award ceremony.

Prof. Roodt received the prize for the high-technology project Development of novel nuclear pharmaceuticals in the Technology and Human Resources for Industry Programme (THRIP).

The Deputy-Minister of Trade and Industry Bongi Maria Ntuli, and Director-General Tshediso Matona presented the prize at the gala dinner held at Gallagher Estate, Gauteng in October 2010.

The dti’s Annual Technology Awards recognise excellence in research and aim to raise awareness on the benefits of using technology to improve the competitiveness of enterprises, within the local and global arena. Individuals and organisations are recognised for their efforts in advancing and promoting technology interests and emerging enterprises.

The technology awards cover the achievements of three of the dti technology programmes collectively, namely THRIP, managed by the National Research Foundation (NRF); the Support Programme for Industrial Innovation (SPII) managed by the Industrial Development Corporation (IDC); and the Small Enterprise Development Agency (seda) Technology Programme (stp).

Prof. Roodt, also vice-president of the European Crystallographic Association, who has just returned from a series of lectures abroad after being elected Fellow of the Royal Society of Chemistry in the UK, has received funding in excess of R3 million over the past two years to set up a specialised laboratory for synthesising active compounds. Key partners in this project are Dr Gerdus Kemp from PETLabs Pharmaceuticals in Pretoria; Prof. Connie Medlen (pharmacologist), recently appointed affiliate professor at UFS Chemistry; as well as Prof. Deon Visser from the Inorganic Chemistry research group at the UFS.

The research aims to produce new nuclear medicinal agents for the early diagnosis of cancer, heart and brain defects, and even HIV/ Aids.

Two doctoral students, Alice Brink and Marietjie Schutte, are currently actively involved in this project. They are the recipients of prestige scholarships introduced by the UFS Rector and Vice-Chancellor, Prof. Jonathan Jansen, under the UFS Research Initiative (the Advanced Biomolecular Systems Cluster) to complete their Ph.D. studies.

Media Release
Issued by: Lacea Loader
Director: Strategic Communication (actg)
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl@ufs.ac.za  
2 November 2010

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