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28 January 2022 | Story Charlene Stanley | Photo Supplied
Prof Francis E Smit has been elected as member of the American Association for Thoracic Surgery (AATS), an elite international organisation whose members have made significant contributions to the care and treatment of cardiothoracic disease throughout the world.

Prof Francis E Smit, Head of the Department of Cardiothoracic Surgery, has become only the third person from sub-Saharan Africa to receive the honour of being elected as a member of the American Association for Thoracic Surgery (AATS).

Stringent membership requirements

The AATS is an august international academic organisation founded more than a century ago by the earliest pioneers in the field of thoracic surgery, to which members are elected according to merit. Membership requires sponsorship and referees from senior and active members, followed by an extensive vetting process by the membership committee.  Currently, the association has more than 1 400 active members from 41 countries. Around 30 to 40 new members are accepted annually, of which only 10 to 15 reside outside the USA and Canada. Successful applicants are selected based on an established international leadership record in the field of cardiothoracic surgery, as demonstrated by their commitment to society and institutions, training and education, research and innovation – including peer-reviewed publications, excellence in patient care, and mentorship of the next generation of cardiothoracic surgeons.

"We are extremely proud of this well-deserved international accolade bestowed on Prof Smit,” said Prof Francis Petersen, Rector and Vice-Chancellor. “Not only does it validate the high standard of cardiothoracic training at the UFS, but also our commitment to multi-disciplinary research and internationalisation."  

Benefits of membership

For Prof Smit, the main benefit of membership lies in the fact that it facilitates high-level collaboration with USA-based researchers and companies, which will contribute towards his vision of making the UFS Department of Cardiothoracic Surgery a leading multi-disciplinary research and training unit with national and international collaborators.

Prof Smit is a firm believer in the potential and relevance of South African research. One of his greatest achievements since his appointment at the UFS in 2004, was the establishment of the interdisciplinary Robert WM Frater Cardiovascular Research Centre in 2015. 

The Frater Centre has three divisions, namely clinical research, bio-engineering, and an integrated multi-disciplinary training and education simulation programme, establishing collaborative research and postgraduate training programmes based on a strategy of interdisciplinary, inter-university, national, and international cooperation. 

World-class cardiovascular research at UFS 

The clinical research division – notably the interdisciplinary cardiomyopathy study group – conducts clinical research in adult and paediatric cardiology and cardiothoracic surgery. The bio-engineering division has developed a patented tissue-engineered de-cellularised bovine pericardial patch for use in cardiovascular and other surgical disciplines. A sub-section of this division conducts research in alternative fixation processes of de-cellularised biological tissue, re-cellularisation and organoid generation, as well as in cardiovascular pharmacology. Research is also being conducted on novel heart valve designs, including testing and evaluation in bench and animal models.  A world-class integrated multi-disciplinary simulation-based education and training system has been developed, catering for African needs and programmes.

News Archive

Breeding of unique game requires a balance between conservation and sustainable use
2014-05-20

 

Game bred for qualities such as unconventional hair colour or horn quality, may on the long term have unexpected consequences for biodiversity and game farming.

This is according to the inaugural lecture of Prof Paul Grobler from the Department of Genetics at the University of the Free State (UFS).

Prof Grobler feels that the consequences of selective breeding should be examined carefully, as there is currently much speculation on the subject without sound scientific information to back it.

“At the moment, colour variation invokes much interest among game farmers and breeders. Unusual colour variants are already available in different game species. These unusual animals usually fetch much higher prices at auctions compared to prices for the ‘normal’ individuals of the species.”

Examples of these unusual variants are springbuck being bred in white, black or copper colours, the black-backed or ‘saddleback’ impala, and the gold-coloured and royal wildebeest.

A black-backed impala was recently sold for R5,7 million.

“Based on genetic theory, good reason exists why these practices need to be monitored, but one should also take care not to make the assumption that selective breeding will inevitably lead to problems,” warns Prof Grobler.

Grobler says that negative characteristics in a species can sometimes unwittingly be expressed during the selection process for a unique colour. “It is seen, for example, in purebred dogs where the breeding of a new race sometimes brings underlying genetic deviations in the species to the front.” He also believes that some of these animals may not be able to adapt to changing environmental conditions.

“However, one should also look at the positive side: because of the good demand for game, including unusual variants, there is much more game in South Africa today than in many decades. Balance should be found between the aims of conservation and the sustainable utilisation of game.”

Research at the UFS’s Department of Genetics is now trying to establish the genetic effects of intensive game breeding and predict the impact on biodiversity.

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