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13 September 2022 | Story Prof Jan du Plessis and André Damons | Photo Istock
Prof_Jan-DuPlessis
Prof Jan du Plessis is the Head of the Paediatric Oncology Unit at the University of the Free State (UFS).

A post on Facebook by a bereaved parent of a young child who tragically died of cancer that reads: “I want my old life back, the one with my child in it”, is unfortunately still the sad reality that many families face, even though in developed countries the overall survival rate for childhood cancer is now over 80%. For some types of cancer and in developing countries such as South Africa, the rate is much lower. There are some childhood cancers for which there is no treatment and which are uniformly fatal. 

Another harsh reality, according to Prof Jan du Plessis, Head of the Paediatric Oncology Unit at the University of the Free State (UFS), is that some of those who do survive cancer can go on to suffer long-term (sometimes life-long) health issues as a result of their treatment. Almost all cancer treatments used in children today were actually developed for adults. Most of these treatments (such as chemotherapy or radiotherapy) target all fast-growing cells (not just cancer cells), and this leads to harsh side-effects in young, growing bodies. 

Prof du Plessis says the need for more effective and safer treatments for children is urgent. Despite better outcomes for children diagnosed with cancer, some do not survive. Currently, between 800 to a 1 000 South African children are diagnosed with cancer annually. However, it’s estimated that half of the children with cancer in South Africa are never diagnosed, according to the Cancer Association of South Africa (CANSA)

Different types of Childhood Cancer

Children can get many different types of cancer. Some of the most common childhood cancers are:
• Leukaemia – cancer of the blood and bone marrow, which is the most common childhood cancer.
• Brain cancer – cancer that grows in the brain which is the second most common childhood cancer. It kills more children than any other type of cancer.
• Neuroblastoma & Nephroblastoma – the most common solid tumours diagnosed in children under the age of five.
• Sarcoma – a cancer that grows in the bones and connective tissues of the body.
• Lymphoma – cancer that develops in the lymphatic system.

St Siluan Warning Signs of Childhood Cancer:

According to CHOC Childhood Cancer Foundation South Africa, research showed that an ongoing awareness campaign on the early warning signs was needed to improve the rate of referrals at an earlier stage of the disease. It is for this reason that 15 February (International Childhood Cancer Day), and the month of September, that marks Childhood Cancer Awareness Month, are important for awareness. 

“It is not possible to prevent cancer in children, but significant improvements can be made in their lives by detecting cancer early and avoiding delays in care. A correct diagnosis is important to treat children with cancer because each cancer involves a specific treatment regimen that may include surgery, radiotherapy, and chemotherapy.

“To improve early diagnosis we try to educate the public/students on the early warning signs of childhood cancer. We use the St Siluan Warning Signs for Childhood Cancer,” explains Prof Du Plessis. 

S – Seek medical help early for ongoing symptoms
I – White spot in the eye, new squint, sudden blindness or bulging eyeball
L – Lump on the stomach, pelvis, head, arms, legs, testicle or glands
U – Unexplained fever present for more than two weeks, weight loss, fatigue, pale appearance, easy bruising and bleeding
A – Aching bones, joints, back and easy fractures
N – Neurological signs, a change in walk, balance or speech, regression, continuous headaches with / without vomiting and enlarged head

According Prof du Plessis, his hope is to diagnose these kids early, the earlier they are diagnosed, the less treatment they are exposed. It is amazing to witness how the cancer kids adapt to their new normal and reality, says Prof Du Plessis. 

“They play soccer in the corridor, not in the park. One in fact learnt to walk in the hospital. Nurses and doctors become their new family. Their joy, strength and resilience is remarkable. Their laughter will make your heart melt. Your life will be forever changed, seeing a child fight cancer.”

News Archive

Suspension of the South African Doping Control Laboratory (SADoCoL) by the World Anti-Doping Agency (WADA)
2016-05-04

The senior leadership of the UFS and the management of the South African Doping Control Laboratory (SADoCoL) take note of the decision by the World Anti-Doping Agency (WADA) to suspend the laboratory’s accreditation to perform doping control analysis on biological samples of athletes and sportsmen and -women until 30 September 2016. During this time of suspension, all sport-related samples will be sent for analysis to the WADA accredited laboratory in Qatar until the accreditation of SADoCoL is re-established. Analysis according to WADA accreditation will therefore not be interrupted during the period of the suspension of the accreditation of SADoCoL.

The announcement by WADA on 3 May 2016 follows a voluntary decision by SADoCoL in March 2016 to temporarily close the laboratory for some of its routine analytical duties for six months, as from 1 April 2016. The decision was taken in consultation with the senior leadership of the UFS and other role players, especially the Department of Sport and Recreation of South Africa (SRSA) and the South African Institute for Drug-Free Sport (SAIDS). SADoCoL is a specialised service laboratory of the University of the Free State (UFS) and has been in existence for more than thirty years.

Due to the ever-increasing demands on the number, variety and analytical sensitivity of compounds to be analysed according to the Prohibited List of WADA, technical and infrastructure adaptations need to be implemented in the laboratory continuously to keep up with the demands. Over the last year, SADoCoL has drastically increased its capacity in both personnel and infrastructure, to a point where these changes can be implemented for optimal performance of the laboratory.  This has to be done while normal routine analysis continues, and it became clear that at present, implementation cannot be successfully accomplished together with the workload from normal routine analyses.

The time of suspension will be utilised to implement and test these new systems in order to achieve the standard presently required by WADA, as well as to perform development and improvements.  This development will be performed in close collaboration with other role players in the anti-doping movement in South Africa, such as SAIDS and SRSA. Scientific development aid will also be acquired from other doping control laboratories worldwide in order to assure that the high analytical quality is maintained and expanded to meet the fast growing challenges in this field. The progress of the process will be closely monitored, and the upgraded methodologies will then, after rigorous testing, be implemented to ensure that the required analytical quality is maintained so as to obtain re-accreditation by WADA at the conclusion of the suspension period.

Issued by: Lacea Loader (Director: Communication and Brand Management)
Telephone: +27(0)51 401 2584 or +27 (0) 83 645 2454
E-mail: news@ufs.ac.za
Fax: +27 (0) 51 444 6393

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