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27 September 2022 | Story André Damons | Photo Charl Devenish
Prof Martin Nyanga
Prof Martin Nyaga, Associate Professor in the UFS-NGS Unit and Director of the WHO Collaborating Centre (WHO CC), says the UFS researchers – through the Division of Virology/NHLS and the UFS-NGS Unit – were involved in the major publication as part of the NGS-SA consortium from the study design phase, ethics applications, and throughout the study.

Researchers from the University of the Free State (UFS) Next Generation Sequencing (UFS-NGS) Unit and Division of Virology/ National Health Laboratory Service (NHLS) were part of a major publication featuring hundreds of authors from Africa who did research on the evolution of SARS-CoV-2.

The scientific publication in the journal Science (impact factor 47.728) featured more than 300 scientists and public health officials from Africa and abroad, who worked together to look into the evolution of SARS-CoV-2, the viral agent causing COVID-19. It was the first collaborative study of this nature conducted in Africa during the COVID-19 global pandemic. The publication became available online on 15 September this year. 

According to a press release by the Centre for Epidemic Response and Innovation (CERI) at Stellenbosch University and the KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) at the University of KwaZulu-Natal (UKZN), this was the largest consortium of African scientists and public health institutions working together to support data-driven COVID-19 response in Africa. This collaboration was led by two labs (CERI and KRISP) and the Network for Genomic Surveillance in South Africa (NGS-SA) consortium, of which the UFS-NGS Unit and Division of Virology are founding members, in close coordination with the Africa CDC, WHO/AFRO and 300 other institutions across the continent.

It is an awesome feeling

Prof Martin Nyaga, Associate Professor in the UFS-NGS Unit and Director of the WHO Collaborating Centre (WHO CC), says the UFS researchers – through the Division of Virology/NHLS (coordinated by Prof Dominique Goedhals and Mr Philip Armand Bester) and also the UFS-NGS Unit (Prof Nyaga, Dr Peter Mwangi, Mr Milton Mogotsi, and Mr Emmanuel Ogunbayo) – were involved as part of the NGS-SA consortium from the study design phase, ethics applications, and throughout the study, processing the SARS-CoV-2 positive samples for whole-genome sequencing, thus generating significant sequence data of the SARS-CoV-2 variants circulating in South Africa.

“It is an awesome feeling to be part of the solution in resolving the COVID-19 pandemic by providing data that would track variants in real time and data used to implement prophylactic solutions, such as vaccine development, against a virus that was a global threat,” says Prof Nyaga. 

According to him, the utility of next-generation sequencing technologies in understanding genomics of diseases was clearly demonstrated in this study and will assist in addressing future diseases/pandemics. These genomic studies provide deeper insights regarding diseases, and they will provide timely solutions to solving diseases affecting the Mother Continent.

UFS Free State variants study

Prof Nyaga says their Free State variants study, which was also recently published in the journal Frontiers in Virology, performed analysis of samples from patients who tested positive for SARS-CoV-2 throughout all the COVID-19 waves. “We aimed to determine whether the variants driving the epidemic waves at the national level were also driving the epidemic waves at the local level, in the context of the Free State province. The data further indicates that SARS-CoV-2 variants driving the epidemic waves in the Free State at the local level correlated with the ones driving the epidemic waves at the national level. Findings from this study highlight the importance of continued genomic surveillance and monitoring of the circulating SARS-CoV-2 variants to inform public health efforts and ensure adequate control of the ongoing pandemic. 

“Our data has been incorporated into the analyses of the bigger continent-wide collaboration on genomics surveillance to determine how the majority of COVID-19 variants were introduced into Africa, which has now been published in the journal Science,” says Prof Nyaga.  
The publication highlights that sustained investment in diagnostics and genomic surveillance in Africa was needed to not only help combat SARS-CoV-2 on the continent, but to establish a platform to address the emerging, re-emerging, endemic infectious disease threats, such as Ebola, HIV/Aids, TB, malaria, and enteric disease-causing viruses.

News Archive

Postgraduate School opens at UFS
2011-05-19

 
Prof. Maresi Nerad, from Washington university in Seattle, USA
Photo: Stephen Collett

We are celebrating the launch of our new Postgraduate School (PGS) on our Main Campus in Bloemfontein from 16 - 20 May 2011.

In line with national priorities for research-based postgraduate education and the focus of the UFS Academic Turnaround Strategy, the aims of the Postgraduate School are to:

  • improve the quality of postgraduate student research;
  • produce graduates who are global citizens, research literate and able to reflect ethically on the purpose, process and product of research;
  • improve throughput rates of postgraduate students; and
  • make the experience of being a postgraduate at the UFS one which is stimulating, enjoyable and which contributes to the development of the person beyond the limits of her or his discipline(s).

“We hope that the school will be a pleasant place to pursue research scholarship, discuss ideas and relax, and we look forward to welcoming postgraduates and other scholars to the school,” Prof. Neil Roos, Director of the UFS Postgraduate School said.

This significant event in the academic transformation of the university goes hand in hand with the inaugural lecture of Prof. Maresi Nerad. Prof. Nerad’s impressive CV reads amongst others that she has a M.A. (Political Science) at the Technical University of Darmstadt, Germany and a Ph.D. (Higher Education) at the University of California, Berkeley. She is also the founding director of the national Center for Innovation and Research Graduate Education (CIRGE).

As Professor Extraordinary in the UFS’s Postgraduate School, she is bringing more to the table than a world of wisdom and her passion for the postgraduate education. “I can contribute lessons learned from four distinct professional experiences, including 17 years of administrative and scholarly leadership in undertaking the conceptual and practical transformational work of organisational change at two US postgraduate schools, where I worked amongst others to improve the quality of mentoring, shorten the time to doctoral degree, and improve doctoral completion rates.”

She also brings to the UFS her experience as founding and current director of the first research center for studies on graduate education in the world. “It is our mission to discover how best to prepare Ph.D. students to be effective leaders in research and society,” she said.

Prof. Nerad says that she is committed to support and consult with the UFS Postgraduate School. She would particularly encourage the use of research to understand postgraduate education in all its dimensions at the UFS better and to use the evidence-based findings as a base for policy-making and resource allocation.

In reflecting on her vision for the UFS Postgraduate School, Prof. Nerad says that five years from now she hopes to see the UFS having strengthened its position as a major driving force in the national South African postgraduate-education community for internationalising postgraduate education. She is also confident that the UFS will supply increased numbers of skilled postgraduates who are “intellectual entrepreneurs and risk takers with a social consciousness, who have sustainability of the systems of the planet as a core value”.

“Five years from now the PSG will have taken the lead in preparing graduate students who are world citizens,” Prof. Nerad concluded.

 

Presentation on PhD students reveals more than meets the eye

British professor presents a discussion at UFS

Journey from student to scholar

Society will take care of interests

Female academics talk about joys and lessons

Research plus the internet equals the cyber scholar
 


 

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